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甲状旁腺移植:人体长期同种异体移植的转归

Parathyroid transplantation: fate of a long-term allograft in man.

作者信息

Ross A J, Dale J K, Gunnells J C, Wells S A

出版信息

Surgery. 1979 Apr;85(4):382-4.

PMID:373147
Abstract

Previously our group reported clinical, histological, and biochemical evidence of parathyroid allograft survival in a patient transplanted sequentially with renal and parathyroid tissues from the same donor. After 30 months of function, both grafts were concomitantly rrjected. The prolonged parathyroid allograft survival described in certain experimental animals has been attributed to the tissue's being "immunologically privileged." Our current clinical observations do not support this hypothesis.

摘要

此前,我们小组报告了一名患者甲状旁腺同种异体移植存活的临床、组织学和生化证据,该患者先后接受了来自同一供体的肾脏和甲状旁腺组织移植。在移植功能发挥30个月后,两个移植物均被同时排斥。某些实验动物中描述的甲状旁腺同种异体移植的长期存活归因于该组织具有“免疫赦免”特性。我们目前的临床观察结果不支持这一假说。

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