Fröhlich M
Stomatol DDR. 1979 Jan;29(1):45-8.
In the GDR, Grisaldon has been used in alveolitis therapy since 1974. The results from the bacteriological testing of this preparation and the diluting and rinsing effects of saliva and blood on it arouse doubts about its antibacterial efficiency. Thrombelastographic studies demonstrated the clotting-accelerating and the marked fibrin-stabilizing effect of pure acetylsalicylic acid. In contrast to other publications, it was stated that the p-hydroxybenzoic acid propyl ester is absolutely indifferent. Histological studies on animals have shown that Grisaldon is detectable in the alveolus as a foreign body even 28 days after application, and that it decelerates wound healing.
在民主德国，自1974年以来，格利沙尔东（Grisaldon）一直用于肺泡炎的治疗。该制剂的细菌学检测结果以及唾液和血液对其的稀释和冲洗作用，引发了对其抗菌效果的质疑。血栓弹力图研究表明，纯乙酰水杨酸具有加速凝血和显著的纤维蛋白稳定作用。与其他出版物不同的是，有人指出对羟基苯甲酸丙酯完全无作用。对动物的组织学研究表明，即使在应用格利沙尔东28天后，在肺泡中仍可将其检测为异物，并且它会延缓伤口愈合。
