• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

肠上皮干细胞向半干细胞转化的不可逆性以及后者自我繁殖的能力

[Irreversibility of intestinal epithelium stem cell conversion into semi-stem enterocytes and the ability of the latter to reproduce themselves].

作者信息

Gushchin V A

出版信息

Tsitologiia. 1979 Jan;21(1):40-5.

PMID:373197
Abstract

The analysis of literature experimental data on cell kinetics of the generating intestinal epithelium of rats and mice suggested the irreversibility of transformation of intestinal epithelium stem cells into non-stem proliferating enterocytes and the ability of the latter for self-reproduction. This property of half-stem enterocytes enabled us to assume that the daughter cells immediately after their appearance are always in the G1-phase of the mother cell mitotic cycle.

摘要

对大鼠和小鼠肠道上皮生成的细胞动力学的文献实验数据进行分析表明，肠道上皮干细胞向非干细胞增殖性肠细胞的转化具有不可逆性，且后者具有自我繁殖能力。半干细胞性肠细胞的这一特性使我们假设，子代细胞在出现后立即始终处于母细胞有丝分裂周期的G1期。

相似文献

1
[Irreversibility of intestinal epithelium stem cell conversion into semi-stem enterocytes and the ability of the latter to reproduce themselves].肠上皮干细胞向半干细胞转化的不可逆性以及后者自我繁殖的能力
Tsitologiia. 1979 Jan;21(1):40-5.
2
Somatic mutation, monoclonality and stochastic models of stem cell organization in the intestinal crypt.肠道隐窝中干细胞组织的体细胞突变、单克隆性及随机模型。
J Theor Biol. 1993 Feb 21;160(4):471-91. doi: 10.1006/jtbi.1993.1031.
3
Cell kinetic studies of the intestinal epithelium: maintenance of the intestinal epithelium in normal and irradiated animals.肠道上皮细胞动力学研究：正常及受辐照动物肠道上皮的维持
Natl Cancer Inst Monogr. 1969 May;30:185-98.
4
[Comparative analysis of the kinetics of populations of enterocytes from different portions of the rat small and large intestine. I. Parameters of the mitotic cycle and heterogeneity of populations of proliferating enterocytes].
Tsitologiia. 1977 Mar;19(3):303-17.
5
The recruitability and cell-cycle state of intestinal stem cells.
Int J Cell Cloning. 1984 Mar;2(2):126-40. doi: 10.1002/stem.5530020206.
6
Effects of 30% intestinal resection on whole population cell kinetics of mouse intestinal epithelium.30%肠切除对小鼠肠上皮全群体细胞动力学的影响。
Anat Rec. 1986 May;215(1):35-41. doi: 10.1002/ar.1092150106.
7
Azoxymethane protects intestinal stem cells and reduces crypt epithelial mitosis through a COX-1-dependent mechanism.氧化偶氮甲烷通过一种COX-1依赖性机制保护肠道干细胞并减少隐窝上皮有丝分裂。
Am J Physiol Gastrointest Liver Physiol. 2006 Dec;291(6):G1062-70. doi: 10.1152/ajpgi.00129.2006. Epub 2006 Oct 12.
8
The stem-cell zone of the small intestinal epithelium. IV. Effects of resecting 30% of the small intestine.小肠上皮的干细胞区。IV. 切除30%小肠的影响。
Am J Anat. 1981 Jan;160(1):93-103. doi: 10.1002/aja.1001600108.
9
[Kinetic dimensions of cells and crypts in irradiated intestinal epithelium of mice].[小鼠辐射肠道上皮细胞和隐窝的动力学维度]
Tsitologiia. 1975 May;27(5):576-9.
10
gamma-Ray-induced apoptosis in transgenic mice with proliferative abnormalities in their intestinal epithelium: re-entry of villus enterocytes into the cell cycle does not affect their radioresistance but enhances the radiosensitivity of the crypt by inducing p53.γ射线诱导的肠道上皮细胞增殖异常的转基因小鼠发生凋亡：绒毛肠上皮细胞重新进入细胞周期并不影响其辐射抗性，但通过诱导p53增强了隐窝的辐射敏感性。
Oncogene. 1997 Jul 10;15(2):131-41. doi: 10.1038/sj.onc.1201176.