Armario A, Lopez-Calderón A
Endocr Res. 1986;12(2):115-22. doi: 10.1080/07435808609035431.
The effect of crowding on the pituitary-gonadal axis was studied in adult male rats. Crowding reduced body weight gain, did not alter relative adrenal weight and increased relative testis weight. Neither basal levels of corticosterone nor its response to acute stress were altered by crowding. Likewise, LH secretion was similar in control and crowded rats. Prolactin levels tended to be lower in crowded than control rats, but they did not reach statistical significance. In contrast, impaired testosterone secretion was observed in crowded rats, at least in part due to reduced Leydig cell responsiveness to gonadotropin release. In addition, some mechanisms other than pituitary-adrenal hyperactivity might be responsible for reduced testosterone secretion during crowding.
在成年雄性大鼠中研究了拥挤对垂体-性腺轴的影响。拥挤会降低体重增加，不改变相对肾上腺重量，但会增加相对睾丸重量。拥挤既不改变皮质酮的基础水平，也不改变其对急性应激的反应。同样，对照大鼠和拥挤大鼠的促黄体生成素分泌相似。拥挤大鼠的催乳素水平往往低于对照大鼠，但未达到统计学显著差异。相比之下，在拥挤大鼠中观察到睾酮分泌受损，至少部分原因是睾丸间质细胞对促性腺激素释放的反应性降低。此外，拥挤期间睾酮分泌减少可能是由垂体-肾上腺功能亢进以外的一些机制导致的。
