深入观察突触：[使得 PSD-95/DLG1 的细胞特异性可视化成为可能。
A closer look at the synapse: ] enables cell-specific visualization of PSD-95/DLG1.
机构信息
Department of Biological Sciences, Southern Illinois University Edwardsville, Edwardsville, IL 62025, USA.
出版信息
Cell Rep Methods. 2023 May 22;3(5):100487. doi: 10.1016/j.crmeth.2023.100487.
Abstract
The PSD-95 homolog, DLG1, is important for excitatory synapse structure and function throughout the nervous system. In this issue of , Parisi et al. present a tool, , that enables cell-specific DLG1 visualization without altering basal synaptic physiology. This tool will potentially enhance our understanding of neuronal development and function in both circuits and individual synapses.
摘要
PSD-95 同源物 DLG1 对于整个神经系统中的兴奋性突触结构和功能都很重要。在本期的 中，Parisi 等人介绍了一种工具 ，它可以实现细胞特异性 DLG1 可视化，而不会改变基础突触生理学。该工具将有可能增强我们对电路和单个突触中神经元发育和功能的理解。
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