Puntambekar Shailesh P, Barse Sharin P, More Shweta A, Goel Arjun, Raj Lakshmi C, Chitale Mihir, Rao T Shantanu, Bharambe Suyog A
Department of Surgery, Galaxy Care Multi Speciality Hospital, Opposite Garware College, Karve Road, Pune, Maharashtra 411004 India.
Galaxy Care Multi Speciality Hospital, Pune, India.
Indian J Surg Oncol. 2023 Jun;14(2):510-517. doi: 10.1007/s13193-023-01709-9. Epub 2023 Feb 24.
A prospective analysis of a retrospective data of patients with cervix carcinoma treated by minimal invasive surgery at high-volume gynecology oncology center analyzing that minimal access surgery is an acceptable treatment modality in cervix carcinoma. The study included 423 patients who underwent laparoscopic/robotic radical hysterectomy after pre-operative evaluation after taking their consent and obtaining ethical approval from the IRB. Post-operatively, patients were followed up at regular intervals for clinical examination and ultrasonography for a median range of 36 months. A PET scan was done only if there was any suspicious finding on clinical examination or ultrasonography. Patients with parametrial involvement, positive vaginal margins, and nodal involvement were treated with chemotherapy/radiotherapy. Four hundred twenty-three patients of cervix carcinoma were treated with minimal access surgery. Average duration of surgeries was 92 min. Median range of duration of post-operative follow-up was 36 months. None of the patients had positive resection margins indicating adequate parametrectomy with complete oncological clearance. On post-operative follow-up, only 2 patients had vaginal recurrence which is comparable to that observed in open surgery and no pelvic recurrence. With the understanding of the anatomical landmarks of the anterior parametrium and development of skills for adequate oncological clearance, minimal access surgery should be the preferred surgical modality in carcinoma of the cervix.
一项对在大型妇科肿瘤中心接受微创手术治疗的宫颈癌患者回顾性数据的前瞻性分析表明,微创手术是宫颈癌可接受的治疗方式。该研究纳入了423例患者,这些患者在获得同意并经机构审查委员会(IRB)伦理批准后,于术前评估后接受了腹腔镜/机器人根治性子宫切除术。术后,定期对患者进行临床检查和超声检查随访,中位随访时间为36个月。仅在临床检查或超声检查发现可疑情况时才进行PET扫描。有宫旁组织受累、阴道切缘阳性和淋巴结受累的患者接受化疗/放疗。423例宫颈癌患者接受了微创手术。手术平均时长为92分钟。术后随访时间的中位范围为36个月。所有患者的切缘均为阴性,表明子宫旁组织切除充分且肿瘤学清除彻底。术后随访中,仅2例患者出现阴道复发,这与开放手术中观察到的情况相当,且无盆腔复发。随着对子宫前侧宫旁组织解剖标志的了解以及充分肿瘤学清除技术的发展,微创手术应成为宫颈癌首选的手术方式。