Ying Jiayun, Cai Xiaodi, Lu Guoping, Chen Weiming
Pediatric ICU, Children's Hospital of Fudan University, Shanghai, China.
Case Rep Crit Care. 2023 Jun 6;2023:2000781. doi: 10.1155/2023/2000781. eCollection 2023.
Sepsis is a critical condition affecting patients worldwide. Systemic inflammatory response syndrome in sepsis contributes to organ dysfunction and mortality. The oXiris is a recently developed continuous renal replacement therapy (CRRT) hemofilter indicated for the adsorption of cytokines from the bloodstream. In our study, in a septic child, CRRT with three filters, including the oXiris hemofilter, resulted in a downregulation of inflammatory biomarkers and a reduction of vasopressors. Herein, we described the first report of such usage in septic children.
脓毒症是一种影响全球患者的危急病症。脓毒症中的全身炎症反应综合征会导致器官功能障碍和死亡。oXiris是一种最近开发的连续性肾脏替代治疗(CRRT)血液滤过器,用于从血液中吸附细胞因子。在我们的研究中,一名脓毒症患儿使用包括oXiris血液滤过器在内的三种滤器进行CRRT,导致炎症生物标志物下调和血管升压药用量减少。在此,我们描述了这种用法在脓毒症患儿中的首例报告。