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使用膜(ST-100、oXiris和M60)对一名脓毒症患儿进行持续肾脏替代治疗

The Use of Membranes (ST-100, oXiris, and M60) for Continuous Renal Replacement Therapy in a Child with Sepsis.

作者信息

Ying Jiayun, Cai Xiaodi, Lu Guoping, Chen Weiming

机构信息

Pediatric ICU, Children's Hospital of Fudan University, Shanghai, China.

出版信息

Case Rep Crit Care. 2023 Jun 6;2023:2000781. doi: 10.1155/2023/2000781. eCollection 2023.

Abstract

Sepsis is a critical condition affecting patients worldwide. Systemic inflammatory response syndrome in sepsis contributes to organ dysfunction and mortality. The oXiris is a recently developed continuous renal replacement therapy (CRRT) hemofilter indicated for the adsorption of cytokines from the bloodstream. In our study, in a septic child, CRRT with three filters, including the oXiris hemofilter, resulted in a downregulation of inflammatory biomarkers and a reduction of vasopressors. Herein, we described the first report of such usage in septic children.

摘要

脓毒症是一种影响全球患者的危急病症。脓毒症中的全身炎症反应综合征会导致器官功能障碍和死亡。oXiris是一种最近开发的连续性肾脏替代治疗(CRRT)血液滤过器,用于从血液中吸附细胞因子。在我们的研究中,一名脓毒症患儿使用包括oXiris血液滤过器在内的三种滤器进行CRRT,导致炎症生物标志物下调和血管升压药用量减少。在此,我们描述了这种用法在脓毒症患儿中的首例报告。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bdfc/10264131/c2812098658c/CRICC2023-2000781.001.jpg

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