School of Optometry, Indiana University, Bloomington, Indiana, USA.
Johnson & Johnson Vision Care Inc., Jacksonville, Florida, USA.
Ophthalmic Physiol Opt. 2023 Sep;43(5):1110-1124. doi: 10.1111/opo.13182. Epub 2023 Jun 16.
Multizone contact lenses control myopia progression by proposed introduction of myopic defocus. This project investigated how much of the pupil area and how many dioptres of myopic defocus are introduced by different lens zone geometries with near- and off-axis viewing.
Ten young myopic adults (18-25 years) binocularly wore four soft contact lenses including a single vision (SV), concentric-ring dual-focus (DF), centre-distance multifocal (MF) and a RingBoost™ (RB) multi-zone design containing a combination of coaxial and non-coaxial zones. A modified aberrometer captured aberrations and pupil sizes at four target vergences between -0.25 and -4.00 D (on-axis) and across the central ±30° of the horizontal retina (off-axis). Defocus was quantified as the difference between the measured refractive state and the target vergence within each zone of a multi-zone design within the pupil and compared with that of equivalent zone areas of the SV lens. The percentage of the pupil containing myopic defocused light for each lens was calculated.
Defocus within the distance correction zones of multi-zone lenses was similar to that of the SV lens. When viewing on-axis at -0.25 D target vergence, on average 11% of the pupil was myopic with SV, whereas 62%, 84% and 50% of the pupil was myopic for the DF, MF and RB designs, respectively. At -4.00 D target vergence, all lenses exhibited a systematic decrease in the percentage of pupil area having myopic defocus (SV: 3%; DF: 18%; MF: 5% and RB: 26%). The off-axis proportions were similar across multi-zone lenses; however, multi-zone lenses retained approximately 1.25-3.0× more myopic defocus than the SV lens.
Subjects accommodated using the distance-correction zones of multi-zone lenses. Multi-zone contact lenses introduced significant myopic defocus on-axis and across the central ±30° retina. However, the magnitude and proportion of defocus were influenced by zone geometry, add power and pupil size.
多焦点隐形眼镜通过引入近视离焦来控制近视进展。本研究旨在探讨不同的镜片区域设计，包括单焦点（SV）、同心环双焦点（DF）、中心距离多焦点（MF）和 RingBoost™（RB）多焦点设计（包含共轴和非共轴区域的组合），在近轴和离轴观察时，能引入多少瞳孔区域和多少屈光度的近视离焦。
10 名年轻近视成年人（18-25 岁）双眼分别佩戴四种软性隐形眼镜，包括单焦点（SV）、同心环双焦点（DF）、中心距离多焦点（MF）和 RingBoost™（RB）多焦点设计（包含共轴和非共轴区域的组合）。改良的像差仪在四个目标屈光度（-0.25 至-4.00 D，在轴上）和水平视网膜中央±30°（离轴）之间，捕获四个目标屈光度下的像差和瞳孔大小。在多焦点设计的每个区域内，将测量的屈光状态与目标屈光度之间的差异量化为离焦，并与 SV 镜片等效区域的离焦进行比较。计算每个镜片的近视离焦光包含的瞳孔百分比。
多焦点镜片的距离矫正区的离焦与 SV 镜片相似。当在-0.25 D 目标离焦的轴上观察时，SV 镜片的瞳孔平均有 11%是近视的，而 DF、MF 和 RB 设计的瞳孔分别有 62%、84%和 50%是近视的。在-4.00 D 目标离焦时，所有镜片的瞳孔区域中近视离焦的比例均呈系统性下降（SV：3%；DF：18%；MF：5%和 RB：26%）。多焦点镜片的离轴比例相似；然而，多焦点镜片保留的近视离焦量比 SV 镜片多 1.25-3.0 倍。
受试者通过多焦点镜片的距离矫正区进行调节。多焦点隐形眼镜在轴上和中央±30°视网膜上引入了显著的近视离焦。然而，离焦的幅度和比例受到区域设计、附加光度和瞳孔大小的影响。
