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疑似 14 世纪墨西哥食源性克氏锥虫病暴发。

Putative 14th Century Outbreak of Foodborne Chagas Disease, Mexico.

机构信息

Artemis One Health Research Foundation, Delft, The Netherlands.

出版信息

Vector Borne Zoonotic Dis. 2023 Jul;23(7):390-392. doi: 10.1089/vbz.2022.0092. Epub 2023 Jun 15.

DOI:10.1089/vbz.2022.0092
PMID:37327016
Abstract

A severe epidemic erupted in Coyoacán at the southern end of Lake Texcoco, in Central Mexico, around 1330. Chroniclers of the 16th century reported that after disrupted fish supply, the inhabitants of Coyoacán had suffered high morbidity and mortality. They developed edema of their eyelids, face, and feet, and hemorrhagic diarrhea. Many died, mainly the young and the old. Pregnant women miscarried. The disease is classically considered an illness of nutritional origin. However, its clinical picture and the circumstances of its emergence are remarkably consistent with an outbreak of foodborne Chagas disease, possibly acquired upon the hunting and consumption of alternative food sources, such as infected opossums ( spp.), unique reservoirs of .

摘要

一场严重的传染病于 1330 年左右在特斯科科湖南端的墨西哥中部的科约阿坎爆发。16 世纪的编年史家报告说,在鱼类供应中断后,科约阿坎的居民发病率和死亡率很高。他们出现了眼睑、面部和脚部水肿以及血性腹泻。许多人死亡,主要是年轻人和老年人。孕妇流产。这种疾病通常被认为是一种营养来源的疾病。然而,它的临床表现和出现的情况与食源性恰加斯病的爆发非常一致,可能是通过猎捕和食用替代食物来源(如受感染的负鼠,唯一的 储存库)而获得的。

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