Division of Ophthalmology, Department of Medicine, Graduate School, Kyung Hee University, Seoul, Korea.
Department of Ophthalmology, Kyung Hee University Hospital at Gangdong, Kyung Hee University School of Medicine, Seoul, Korea.
Medicine (Baltimore). 2023 Jun 16;102(24):e33920. doi: 10.1097/MD.0000000000033920.
Plasmacytoma is a disease caused by the proliferation of monoclonal immunoglobulin-producing plasma cells and divided into multiple myeloma, solitary bone plasmacytoma, and extramedullary plasmacytoma. We report a case of orbital extramedullary plasmacytoma invading the dura mater in a patient with exophthalmos and diplopia.
A 35-year-old female patient with exophthalmos in the right eye and diplopia visited the clinic.
The thyroid function tests showed nonspecific results. Orbital computed tomography and magnetic resonance imaging revealed a homogeneously enhancing orbital mass infiltrating the right maxillary sinus and adjacent brain tissue in the middle cranial fossa through the superior orbital fissure.
To diagnose and alleviate the symptoms, an excisional biopsy was performed, which revealed a plasmacytoma.
One month after the surgery, the protruding symptoms and eye movement restriction in the right eye improved, and the visual acuity in the right eye was restored.
In this case report, we present a case of an extramedullary plasmacytoma that originated in the inferior wall of the orbit and invaded the cranial cavity. To our knowledge, no previous reports have described a solitary plasmacytoma that originated in the orbit, causing exophthalmos and invading the cranial cavity at the same time.
浆细胞瘤是由单克隆免疫球蛋白产生的浆细胞增殖引起的疾病，分为多发性骨髓瘤、孤立性骨浆细胞瘤和髓外浆细胞瘤。我们报告了一例眼眶髓外浆细胞瘤侵犯硬脑膜的病例，患者表现为眼球突出和复视。
一位 35 岁女性患者因右眼眼球突出和复视就诊。
甲状腺功能检查结果无特异性。眼眶 CT 和磁共振成像显示，一个均匀增强的眶内肿块通过眶上裂侵入右侧上颌窦和中颅窝邻近脑组织。
为明确诊断并缓解症状，进行了切除活检，结果显示为浆细胞瘤。
术后 1 个月，右眼突出症状和眼球运动受限改善，右眼视力恢复。
在本病例报告中，我们介绍了一例起源于眼眶下壁并侵犯颅腔的髓外浆细胞瘤。据我们所知，以前没有报道过孤立性浆细胞瘤起源于眼眶，同时引起眼球突出并侵犯颅腔。
