牙龈肿瘤：巴西 888 例患者的多中心协作研究。
Gingival neoplasms: a multicenter collaborative study of 888 patients in Brazil.
机构信息
Universidade Federal de Pernambuco Departamento de Clínica e Odontologia Preventiva 4ª Travessa Professor Artur de Sá, s/n. Cidade Universitária CEP: 50740-521, Recife, Pernambuco, Brazil
出版信息
Med Oral Patol Oral Cir Bucal. 2023 Jul 1;28(4):e301-e309. doi: 10.4317/medoral.25707.
BACKGROUND
To evaluate the prevalence and clinicopathological features of a large series of gingival neoplasms in Brazil.
MATERIAL AND METHODS
All gingival benign and malignant neoplasms were retrieved from the records of six Oral Pathology Services in Brazil, during a 41-year period. Clinical and demographic data, clinical diagnosis, and histopathological data were collected from the patients' clinical charts. For statistical analysis, the chi-square, median test of independent samples and the U Mann-Whitney tests were used, considering a significance of 5%.
RESULTS
From 100,026 oral lesions, 888 (0.9%) were gingival neoplasms. There were 496 (55.9%) males, with a mean age of 54.2 years. Most cases (70.3%) were malignant neoplasms. Nodules (46.2%) and ulcers (38.9%) were the most common clinical appearance for benign and malignant neoplasms, respectively. Squamous cell carcinoma (55.6%) was the most common gingival neoplasm, followed by squamous cell papilloma (19.6%). In 69 (11.1%) malignant neoplasms, the lesions were clinically considered to be inflammatory or of infectious origin. Malignant neoplasms were more common in older men, appeared with larger size, and with a time of complaint shorter than benign neoplasms (p<0.001).
CONCLUSIONS
Benign and malignant tumors may appear as nodules in gingival tissue. In addition, malignant neoplasms, especially squamous cell carcinoma, should be considered in the differential diagnosis of persistent single gingival ulcers.
背景
评估巴西一系列大型牙龈肿瘤的患病率和临床病理特征。
材料与方法
从巴西六家口腔病理服务机构的记录中检索到所有牙龈良性和恶性肿瘤，时间跨度为 41 年。从患者的临床病历中收集临床和人口统计学数据、临床诊断和组织病理学数据。为了进行统计分析，使用了卡方检验、独立样本中位数检验和 U 曼-惠特尼检验，置信水平为 5%。
结果
从 100026 例口腔病变中，888 例（0.9%）为牙龈肿瘤。其中 496 例（55.9%）为男性，平均年龄为 54.2 岁。大多数病例（70.3%）为恶性肿瘤。良性和恶性肿瘤中最常见的临床表现分别为结节（46.2%）和溃疡（38.9%）。鳞状细胞癌（55.6%）是最常见的牙龈肿瘤，其次是鳞状细胞乳头状瘤（19.6%）。在 69 例（11.1%）恶性肿瘤中，病变在临床上被认为是炎症或感染性起源。恶性肿瘤在老年男性中更为常见，且肿瘤体积较大，症状持续时间较良性肿瘤短（p<0.001）。
结论
良性和恶性肿瘤可能在牙龈组织中表现为结节。此外，在持续性单个牙龈溃疡的鉴别诊断中，应考虑恶性肿瘤，尤其是鳞状细胞癌。
Zotero 插件