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坦桑尼亚反复发生慢性扁桃体炎和阻塞性睡眠呼吸暂停的儿童在接受(腺样体)扁桃体切除术时,其扁桃体内表面和核心的细菌定植情况。

Bacterial colonisation of surface and core of palatine tonsils among Tanzanian children with recurrent chronic tonsillitis and obstructive sleep apnoea who underwent (adeno)tonsillectomy.

机构信息

Department of Otolaryngology, Kilimanjaro Christian Medical Centre, Kilimanjaro, Tanzania.

Department of Otolaryngology, Kilimanjaro Christian Medical University College, Kilimanjaro, Tanzania.

出版信息

J Laryngol Otol. 2024 Jan;138(1):89-92. doi: 10.1017/S0022215123001147. Epub 2023 Jun 19.

DOI:10.1017/S0022215123001147
PMID:37332170
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10772025/
Abstract

OBJECTIVE

Acute and chronic tonsillitis are frequently treated with antibiotics. This study aimed to understand the presence of pathogenic micro-organisms on the surface and core of chronically infected tonsils among Tanzanian children.

METHODS

The study enrolled children undergoing adenotonsillectomy. Surface and core tonsillar swabs were taken. Quantitative polymerase chain reaction was performed for , , , , and .

RESULTS

Surface and core combined, isolated (86.1 per cent) was found the most, followed by (74.9 per cent), (42.6 per cent) and (28.7 per cent). and were only found in a few patients, 5.6 per cent and 0.8 per cent respectively.

CONCLUSION

Colonisation of the tonsillar surface and core has been found. Potentially pathogenic micro-organisms are likely to be missed based on a throat swab. Hence, the practice of surface tonsillar swabbing may be misleading or insufficient.

摘要

目的

急性和慢性扁桃体炎常采用抗生素治疗。本研究旨在了解坦桑尼亚儿童慢性感染扁桃体表面和核心存在的致病微生物。

方法

本研究纳入行扁桃体腺样体切除术的儿童。采集扁桃体表面和核心拭子。采用聚合酶链反应进行定量检测 、 、 、 、 。

结果

表面和核心联合培养,发现 (86.1%)最常见,其次是 (74.9%)、 (42.6%)和 (28.7%)。 和 仅在少数患者中发现,分别为 5.6%和 0.8%。

结论

已发现扁桃体表面和核心定植。根据咽拭子可能会遗漏潜在的致病微生物。因此,扁桃体表面拭子的做法可能具有误导性或不充分。

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