Marznaki Zohreh Hosseini, Emami Zeydi Amir, Ghazanfari Mohammad Javad, Salisu Waliu Jawula, Amiri Mehdi Mohammadian, Karkhah Samad
Imam Ali Hospital, Mazandaran University of Medical Sciences, Sari, Iran.
Department of Medical-Surgical Nursing, Nasibeh School of Nursing and Midwifery, Mazandaran University of Medical Sciences, Sari, Iran.
Iran J Nurs Midwifery Res. 2023 Apr 14;28(2):123-131. doi: 10.4103/ijnmr.ijnmr_310_21. eCollection 2023 Mar-Apr.
Medication Error (ME) is a major patient safety concern in Intensive Care Units (ICUs). Critical care nurses play a crucial role in the safe administration of medication. This study was conducted to comprehensively review the literature concerning the prevalence of ME and associated factors and outcomes in Iranian ICU nurses.
An extensive search of the literature was carried in international databases including PubMed, Web of Science, Scopus, and Google Scholar, as well as Persian databases such as Magiran and Scientific Information Database (SID) using ME-related keywords and the Persian equivalent of these keywords, from the first article written in this field to artcles published on March 30, 2021. The appraisal tool (AXIS tool) was used to assess the quality of the included studies.
Fifteen studies were included in this systematic review. The prevalence of MEs made by ICU nurses was 53.34%. The most common types of MEs were wrong infusion rate (14.12%), unauthorized medication (11.76%), and wrong time (8.49%) errors, respectively. MEs occurred more frequently in morning work shifts (44.44%). MEs happened more frequently for heparin, vancomycin, ranitidine, and amikacin. The most important influential factor in the occurrence of MEs in ICUs was management and human factors.
The prevalence of MEs made by Iranian ICU nurses is high. Therefore, nurse managers and policymakers should develop appropriate strategies, including training programs, to reduce the occurrence of MEs made by nurses in ICUs.
用药错误（ME）是重症监护病房（ICU）中主要的患者安全问题。重症监护护士在安全给药方面起着至关重要的作用。本研究旨在全面回顾有关伊朗ICU护士用药错误的发生率、相关因素及后果的文献。
在国际数据库（包括PubMed、科学网、Scopus和谷歌学术）以及波斯语数据库（如Magiran和科学信息数据库（SID））中，使用与用药错误相关的关键词以及这些关键词的波斯语等效词，对从该领域撰写的第一篇文章到2021年3月30日发表的文章进行广泛的文献检索。评估工具（AXIS工具）用于评估纳入研究的质量。
本系统评价纳入了15项研究。ICU护士发生用药错误的发生率为53.34%。最常见的用药错误类型分别是输液速度错误（14.12%）、未经授权用药（11.76%）和时间错误（8.49%）。用药错误在早班工作期间发生得更频繁（44.44%）。肝素、万古霉素、雷尼替丁和阿米卡星发生用药错误的频率更高。ICU中发生用药错误的最重要影响因素是管理和人为因素。
伊朗ICU护士发生用药错误的发生率很高。因此，护士管理者和政策制定者应制定适当的策略, 包括培训计划，以减少ICU护士发生用药错误的情况。
