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甲基苯丙胺所致低血糖症:一例报告及文献综述

Methamphetamine-Induced Hypoglycemia: A Case Report and Literature Review.

作者信息

Ghantarchyan Henrik, Fischer Nina, Karp David, Hamidi Afshin

机构信息

Internal Medicine, Arrowhead Regional Medical Center, Colton, USA.

Endocrinology and Diabetes, Arrowhead Regional Medical Center, Colton, USA.

出版信息

Cureus. 2023 May 17;15(5):e39158. doi: 10.7759/cureus.39158. eCollection 2023 May.

Abstract

We present a rare case of a 34-year-old male patient with a history of schizophrenia who was found to be persistently hypoglycemic after a positive toxicology screen for methamphetamine. The patient has had multiple admissions to the hospital for persistent hypoglycemia and was then transferred to our in-patient behavioral health unit (BHU). At this time, his toxicology screen was negative for methamphetamines. During his stay in the BHU, he was compliant with his psychiatric medications and was euglycemic despite having a poor appetite until he was discharged home. This patient was shortly readmitted to the hospital and found to be severely hypoglycemic and methamphetamine positive. Here, we present this rare case of methamphetamine-induced hypoglycemia. We emphasize our work-up, treatment, and our suggested theory of why methamphetamines are the likely cause of hypoglycemia.

摘要

我们报告了一例罕见病例,一名34岁男性精神分裂症患者,在甲基苯丙胺毒理学筛查呈阳性后被发现持续低血糖。该患者因持续性低血糖多次入院,随后被转入我们的住院行为健康科(BHU)。此时,他的甲基苯丙胺毒理学筛查呈阴性。在他住院期间,他按医嘱服用精神科药物,尽管食欲不佳,但血糖正常,直至出院回家。该患者不久后再次入院,被发现严重低血糖且甲基苯丙胺检测呈阳性。在此,我们展示了这例罕见的甲基苯丙胺诱发低血糖病例。我们强调了我们的检查、治疗过程,以及我们提出的关于甲基苯丙胺为何可能是低血糖病因的理论。

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本文引用的文献

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Clinical review: Drug-induced hypoglycemia: a systematic review.临床综述:药物性低血糖症:一项系统综述
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Methamphetamine-induced insulin release.甲基苯丙胺诱导的胰岛素释放。
Science. 1971 Oct 1;174(4004):66-8. doi: 10.1126/science.174.4004.66.

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