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复杂钙化病变的治疗:斑块修饰策略

Treatment of Difficult, Calcified Lesions: Plaque Modification Strategies.

作者信息

Haddad Mustafa, Scheidt Matthew J

机构信息

Division of Vascular and Interventional Radiology, Department of Radiology, Medical College of Wisconsin, Milwaukee, Wisconsin.

出版信息

Semin Intervent Radiol. 2023 Jun 16;40(2):136-143. doi: 10.1055/s-0043-1768678. eCollection 2023 Apr.

DOI:10.1055/s-0043-1768678
PMID:37333746
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10275677/
Abstract

Endovascular management of peripheral arterial disease is continually evolving. Most changes focus on addressing the challenges that hinder optimal patient outcomes; one of the most significant is how to best treat calcified lesions. Hardened plaque results in a variety of technical issues including impaired device delivery, decreased luminal revascularization, poor stent expansion, heightened risk of in-stent stenosis or thrombosis, and increased procedural time and cost. For this reason, plaque modification devices have been developed to mitigate this issue. This paper will describe these strategies and provide the reader with an overview of devices that can be used to treat chronically hardened lesions.

摘要

外周动脉疾病的血管内治疗方法在不断发展。大多数变化都集中在应对那些阻碍实现最佳患者治疗效果的挑战上;其中最显著的挑战之一就是如何最好地治疗钙化病变。硬化斑块会引发一系列技术问题,包括器械输送受损、管腔再血管化程度降低、支架扩张不良、支架内狭窄或血栓形成风险增加,以及手术时间延长和成本增加。因此,已开发出斑块改良器械来缓解这一问题。本文将描述这些策略,并为读者概述可用于治疗长期硬化病变的器械。

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Jetstream Atherectomy Followed by Paclitaxel-Coated Balloons versus Balloon Angioplasty Followed by Paclitaxel-Coated Balloons: Twelve-Month Exploratory Results of the Prospective Randomized JET-RANGER Study.喷射血栓切除术联合紫杉醇涂层球囊与球囊血管成形术联合紫杉醇涂层球囊治疗:前瞻性随机 JET-RANGER 研究的 12 个月探索性结果。
Vasc Health Risk Manag. 2022 Aug 2;18:603-615. doi: 10.2147/VHRM.S371177. eCollection 2022.
2
Randomized Trial of Chocolate Touch Compared With Lutonix Drug-Coated Balloon in Femoropopliteal Lesions (Chocolate Touch Study).巧克力触摸与 Lutonix 药物涂层球囊治疗股腘病变的随机对照试验(巧克力触摸研究)。
Circulation. 2022 May 31;145(22):1645-1654. doi: 10.1161/CIRCULATIONAHA.122.059646. Epub 2022 Apr 4.
3
Prospective Study of Serration Angioplasty in the Infrapopliteal Arteries Using the Serranator Device: PRELUDE BTK Study.采用 Serranator 装置行锯齿样扩张成形术治疗小腿动脉病变的前瞻性研究:PRELUDE BTK 研究。
J Endovasc Ther. 2022 Aug;29(4):586-593. doi: 10.1177/15266028211059917. Epub 2021 Nov 20.
4
Intravascular Lithotripsy for Treatment of Calcified Infrapopliteal Lesions: Results from the Disrupt PAD III Observational Study.血管内碎石术治疗钙化性下肢动脉病变:Disrupt PAD III 观察性研究结果。
J Endovasc Ther. 2022 Feb;29(1):76-83. doi: 10.1177/15266028211032953. Epub 2021 Aug 12.
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Intravascular Lithotripsy for Peripheral Artery Calcification: 30-Day Outcomes From the Randomized Disrupt PAD III Trial.血管内碎石术治疗外周动脉钙化:随机 Disrupt PAD III 试验的 30 天结果。
JACC Cardiovasc Interv. 2021 Jun 28;14(12):1352-1361. doi: 10.1016/j.jcin.2021.04.010.
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Calcium Modification Techniques in Complex Percutaneous Coronary Intervention.复杂经皮冠状动脉介入治疗中的钙修饰技术。
Circ Cardiovasc Interv. 2021 May;14(5):e009870. doi: 10.1161/CIRCINTERVENTIONS.120.009870. Epub 2021 Jan 14.
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