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足部畸形与糖尿病足之间的影像学测量相关性分析

Correlation analysis between foot deformity and diabetic foot with radiographic measurement.

作者信息

Luo Xu, Zhang Chun, Huang Qiuhong, Du Zhipeng, Ni Xia, Zeng Qinglian, Cheng Qingfeng

机构信息

Department of Endocrinology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.

School of Public Health and Management, Chongqing Medical University, Chongqing, China.

出版信息

Front Clin Diabetes Healthc. 2023 Jun 2;4:1121128. doi: 10.3389/fcdhc.2023.1121128. eCollection 2023.

Abstract

BACKGROUND

Foot deformity is a risk factor for diabetic foot ulcer. This study was aimed to investigate the relationship between hallux valgus (HV) and diabetic foot through the radiographic measurement.

METHODS

The patients with diabetic foot hospitalizing in the Department of Endocrinology, the First Affiliated Hospital of Chongqing Medical University from September 2016 to June 2020 were selected. Then the foot plain X-ray radiographs were completed, and the size of HV angle (HVA) was measured. Their clinical data were collected, and the ulcer recurrence rate, amputation rate and mortality rate of the patients were followed up.

RESULTS

A total of 370 patients were included. According to HVA, patients were divided into non-HV group (HVA<15°), and mild (15°≤HVA ≤ 20°), moderate (20°<HVA ≤ 40°) and severe (HVA>40°) HV groups. The age, height, BMI, smoking history and glycosylated hemoglobin level among the non-HVA, mild, moderate, and severe HV group (P<0.05), while smoking history, HbA1c, eGFR and autonomic neuropathy were significantly lower in HV group than those in non-HV group (P<0.05). The ulcer area in patients with moderate HV was larger than that in non-HV patients, and the severity of infection in patients with severe HV was significantly higher than that the other three groups (P<0.05).

CONCLUSION

The occurrence of HV is not only related to age and BMI, but also to the creatinine and eGFR level, autonomic neuropathy, lower limb arteriosclerosis occlusion, coronary heart disease and hypertension. Therefore, more attention should be paid to renal function screening, neuropathy screening and evaluation of lower extremity vascular lesions in patients with diabetes, especially those with moderate or higher HV.

摘要

背景

足部畸形是糖尿病足溃疡的一个危险因素。本研究旨在通过影像学测量探讨拇外翻(HV)与糖尿病足之间的关系。

方法

选取2016年9月至2020年6月在重庆医科大学附属第一医院内分泌科住院的糖尿病足患者。然后完成足部X线平片检查,测量HV角(HVA)的大小。收集他们的临床资料,并对患者的溃疡复发率、截肢率和死亡率进行随访。

结果

共纳入370例患者。根据HVA,将患者分为非HV组(HVA<15°),轻度(15°≤HVA≤20°)、中度(20°<HVA≤40°)和重度(HVA>40°)HV组。非HVA组、轻度、中度和重度HV组之间的年龄、身高、体重指数、吸烟史和糖化血红蛋白水平(P<0.05),而HV组的吸烟史、糖化血红蛋白、估算肾小球滤过率和自主神经病变明显低于非HV组(P<0.05)。中度HV患者的溃疡面积大于非HV患者,重度HV患者的感染严重程度明显高于其他三组(P<0.05)。

结论

HV的发生不仅与年龄和体重指数有关,还与肌酐和估算肾小球滤过率水平、自主神经病变、下肢动脉硬化闭塞、冠心病和高血压有关。因此,对于糖尿病患者,尤其是中度或以上HV患者,应更加重视肾功能筛查、神经病变筛查和下肢血管病变评估。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/baac/10275571/dfee9d9e4a09/fcdhc-04-1121128-g001.jpg

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