Harris Sarah L, McKinlay Chris, Groom Katie, Beker Friederike, Kochar Anuradha, Gill Andrew
University of Otago, Christchurch, New Zealand.
Canterbury District Health Board, Christchurch, New Zealand.
J Pediatr X. 2019 Nov 20;1:100009. doi: 10.1016/j.ympdx.2019.100009. eCollection 2019 Spring.
We evaluated the effect of antenatal sildenafil on neonatal cardiovascular function in a subgroup of 27 infants of mothers participating in the STRIDER-NZAus randomized controlled trial. In this small study, we found no association between antenatal sildenafil and neonatal cardiac dysfunction including no pulmonary hypertension in exposed or unexposed infants.
我们在参与STRIDER-NZAus随机对照试验的母亲所生的27名婴儿亚组中,评估了产前使用西地那非对新生儿心血管功能的影响。在这项小型研究中,我们发现产前使用西地那非与新生儿心脏功能障碍之间没有关联,包括暴露组和未暴露组婴儿均未出现肺动脉高压。