Assistant professor of cardiovascular medicine, cardiovascular department, faculty of Medicine, Tanta University, EG.
Lecturer of endocrinology, internal medicine department, faculty of Medicine, Tanta University, EG.
Glob Heart. 2023 Jun 14;18(1):31. doi: 10.5334/gh.1211. eCollection 2023.
Hypertension is a leading problem; it affects around thirty million adult Egyptians, according to the last national registry. The exact prevalence of resistant hypertension (RH) in Egypt wasn't spotted before. The purpose of this study was to determine the prevalence, predictors, and impact on adverse cardiovascular outcomes among adult Egyptians with RH.
The present study examined a cohort of 990 hypertensive patients who were divided into two groups based on their blood pressure control; group I (n = 842) patients who achieved blood pressure control and group II (n = 148) patients who met the RH definition criteria. All patients underwent a close follow-up for one year to evaluate the major cardiovascular events.
The prevalence of RH was 14.9%. The main predictors impacting the cardiovascular outcomes of RH were advanced age (≥65 years), the presence of chronic kidney diseases, a BMI ≥ 30 kg/m, and NSAID use. After one year of follow-up, the RH group displayed noticeably higher rates of major cardiovascular events, including new-onset atrial fibrillation (6.8% vs. 2.5%, P = 0.006), cerebral stroke (4.1% vs. 1.2%, P = 0.011), myocardial infarction (4.7% vs. 1.3%, P = 0.004), and acute heart failure (4.7% vs. 1.8%, P = 0.025).
The prevalence of RH in Egypt is moderately high. Patients with RH have a far higher risk of cardiovascular events than those whose blood pressure is within control.
高血压是一个主要问题；根据最近的国家登记，它影响了大约 3000 万埃及成年人口。以前没有发现埃及确切的耐药性高血压（RH）的患病率。本研究的目的是确定埃及成年 RH 患者的患病率、预测因素及其对不良心血管结局的影响。
本研究检查了 990 例高血压患者的队列，根据血压控制情况将他们分为两组；第 I 组（n = 842）患者血压得到控制，第 II 组（n = 148）患者符合 RH 定义标准。所有患者接受了为期一年的密切随访，以评估主要心血管事件。
RH 的患病率为 14.9%。影响 RH 心血管结局的主要预测因素是年龄较大（≥65 岁）、存在慢性肾脏疾病、BMI≥30kg/m 和 NSAID 用药。经过一年的随访，RH 组主要心血管事件的发生率明显更高，包括新发心房颤动（6.8% vs. 2.5%，P=0.006）、脑卒（4.1% vs. 1.2%，P=0.011）、心肌梗死（4.7% vs. 1.3%，P=0.004）和急性心力衰竭（4.7% vs. 1.8%，P=0.025）。
埃及 RH 的患病率中等偏高。RH 患者发生心血管事件的风险远高于血压控制患者。
