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继发性高血压作为治疗抵抗的原因。

Secondary hypertension as a cause of treatment resistance.

机构信息

Department of Cardiology, University Hospital Zurich (USZ) and University of Zurich (UZH), Zurich Switzerland.

Department of Endocrinology, Diabetology and Clinical Nutrition, University Hospital Zurich (USZ) and University of Zurich (UZH), Zurich Switzerland.

出版信息

Blood Press. 2023 Dec;32(1):2224898. doi: 10.1080/08037051.2023.2224898.

Abstract

In secondary hypertension, elevated blood pressure is caused by a known and/or potentially treatable underlying disease.Although the prevalence of secondary hypertension depends on the patient population and the thoroughness of applied diagnostic approaches, arterial hypertension is classified in 90 to 95% as primary in nature. In young patients, individuals without a family history of hypertension, late onset of hypertension or worsening of a previous well-controlled hypertension as well as in patients who have a difficult to treat hypertension, the prevalence of secondary hypertension is significantly higher.Because the identification and the specific therapy of secondary hypertension may result in normalisation or improvement of elevated blood pressure in many cases, a targeted diagnostics is of great importance.

摘要

在继发性高血压中,升高的血压是由已知和/或潜在可治疗的基础疾病引起的。尽管继发性高血压的患病率取决于患者人群和应用诊断方法的彻底性,但动脉高血压在 90%至 95%的情况下被归类为原发性。在年轻患者、无高血压家族史、高血压发病较晚或以前控制良好的高血压恶化的患者以及治疗困难的高血压患者中,继发性高血压的患病率明显更高。由于识别和特定的继发性高血压治疗可能导致许多情况下升高的血压正常化或改善,因此有针对性的诊断具有重要意义。

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