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用于治疗子宫性不孕症的组织再生工程现状

Current Status of Tissue Regenerative Engineering for the Treatment of Uterine Infertility.

作者信息

Huang Di, Liang Junhui, Yang Jie, Yang Chunrun, Wang Xin, Dai Tianyu, Steinberg Thorsten, Li Changzhong, Wang Fei

机构信息

Shandong First Medical University, Jinan, China.

Departments of Obstetrics and Gynecology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China.

出版信息

Tissue Eng Part B Rev. 2023 Oct;29(5):558-573. doi: 10.1089/ten.TEB.2022.0226. Epub 2023 Sep 26.

Abstract

With the recent developments in tissue engineering, scientists have attempted to establish seed cells from different sources, create cell sheets through various technologies, implant them on scaffolds with various spatial structures, or load scaffolds with cytokines. These research results are very optimistic, bringing hope to the treatment of patients with uterine infertility. In this article, we reviewed articles related to the treatment of uterine infertility from the aspects of experimental treatment strategy, seed cells, scaffold application, and repair criteria so as to provide a basis for future research.

摘要

随着组织工程学的最新发展,科学家们试图从不同来源建立种子细胞,通过各种技术创建细胞片,将其植入具有各种空间结构的支架上,或在支架上负载细胞因子。这些研究结果非常乐观,为子宫性不孕患者的治疗带来了希望。在本文中,我们从实验治疗策略、种子细胞、支架应用和修复标准等方面综述了与子宫性不孕治疗相关的文章,以便为未来的研究提供依据。

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