From the Department of Nuclear Medicine and Minnan PET Center, Xiamen Cancer Center.
Department of Rehabilitation Medicine, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China.
Clin Nucl Med. 2023 Sep 1;48(9):809-811. doi: 10.1097/RLU.0000000000004748. Epub 2023 Jun 17.
Benign metastasizing leiomyomas (BMLs) are benign disseminated extrauterine tumors in patients with prior history of uterine leiomyomas and may occur years after hysterectomy. In this case, we presented 18 F-FDG and 68 Ga-FAPI PET/CT findings in a 37-year-old woman with benign leiomyoma metastasizing to lung and pelvis. The metastatic lesions demonstrated faint 18 F-FDG but elevated 68 Ga-FAPI activity, indicating the low level of glucose metabolism but excessive accumulation of activated fibroblasts in the BMLs. This case demonstrated that 68 Ga-FAPI PET/CT may be potentially useful in the evaluation of BMLs.
良性转移性平滑肌瘤（BML）是指既往有子宫平滑肌瘤病史的患者体内良性播散性子宫外肿瘤，可在子宫切除术多年后发生。在此例中，我们展示了一位 37 岁女性的 18 F-FDG 和 68 Ga-FAPI PET/CT 结果，该患者良性平滑肌瘤转移至肺部和骨盆。转移病灶显示出微弱的 18 F-FDG 摄取，但 68 Ga-FAPI 活性升高，提示 BML 中葡萄糖代谢水平较低，但激活的成纤维细胞过度积聚。本病例表明，68 Ga-FAPI PET/CT 可能在评估 BML 方面具有潜在的应用价值。
