Department of General Surgery 1, The Affiliated Hospital of Chengde Medical University, Chengde, Hebei, China.
Department of Pediatric Medicine, The Affiliated Hospital of Chengde Medical University, Chengde, Hebei, China.
Medicine (Baltimore). 2023 May 19;102(20):e33759. doi: 10.1097/MD.0000000000033759.
This study aimed to explore the risk factors of clinically relevant pancreatic fistulas (PF) after laparoscopic pancreaticoduodenectomy (LPD). The clinical data of 80 patients who underwent pancreaticoduodenectomy in our hospital were retrospectively analyzed. The potential risk factors for PF after LPD were determined using univariate and multivariate logistic regression analyses. Results from the univariate analyses showed that the pancreatic duct diameter (P < .001), pancreatic texture (P < .001), abdominal infection (P = .002), and reoperation (P < .001) were associated with clinically relevant PF. Results from the multivariate logistic regression analysis showed that the pancreatic duct diameter (P = .002) and pancreatic texture (P = .016) were significant risk factors for clinically relevant PF. Based on this study, the pancreatic duct diameter and pancreatic texture are independent risk factors for clinically relevant PF after LPD.
本研究旨在探讨腹腔镜胰十二指肠切除术（LPD）后临床相关胰瘘（PF）的危险因素。回顾性分析了我院 80 例行胰十二指肠切除术患者的临床资料。采用单因素和多因素 logistic 回归分析确定 LPD 后 PF 的潜在危险因素。单因素分析结果显示，胰管直径（P<0.001）、胰腺质地（P<0.001）、腹部感染（P=0.002）和再次手术（P<0.001）与临床相关 PF 有关。多因素 logistic 回归分析结果表明，胰管直径（P=0.002）和胰腺质地（P=0.016）是临床相关 PF 的显著危险因素。基于本研究，胰管直径和胰腺质地是 LPD 后临床相关 PF 的独立危险因素。
