Sandoval Ivett Karina, Ngoh Gwendolyn, Wu Jia, Crowley Michael J, Rutherford Helena J V
Yale Child Study Center, Yale University, New Haven, CT, USA.
Yale Child Study Center, Yale University, New Haven, CT, USA.
Brain Res. 2023 Oct 1;1816:148468. doi: 10.1016/j.brainres.2023.148468. Epub 2023 Jun 17.
During pregnancy and the postpartum period, changes in brain volume and in motivational, sensory, cognitive, and emotional processes have been described. However, to date, longitudinal modifications of brain function have been understudied. To explore regional cortical coupling, in pregnancy and at 3 months postpartum, we analyzed resting-state electroencephalographic (EEG) coherence in the delta, theta, alpha, alpha, beta, and beta frequency bands across frontal and parietal regions of the maternal brain (Fp1, Fp2, F3, F4, P3, and P4). We found that from pregnancy to the postpartum period, mothers showed less intrahemispheric EEG coherence between the frontal and parietal regions in the alpha and alpha bands, as well as greater interhemispheric EEG coherence between frontopolar regions in the beta band. These changes suggest decreased inhibition of neural circuits. These neurophysiological changes may represent an adaptive process characteristic of motherhood.
在孕期和产后期间，大脑体积以及动机、感觉、认知和情感过程都发生了变化。然而，迄今为止，大脑功能的纵向变化一直未得到充分研究。为了探究区域皮质耦合，我们在孕期和产后3个月，分析了产妇大脑额叶和顶叶区域（Fp1、Fp2、F3、F4、P3和P4）在δ、θ、α、α、β和β频段的静息态脑电图（EEG）连贯性。我们发现，从孕期到产后，母亲在α和α频段的额叶和顶叶区域之间的半球内EEG连贯性降低，以及在β频段额极区域之间的半球间EEG连贯性增加。这些变化表明神经回路的抑制作用减弱。这些神经生理变化可能代表了母性的一种适应性过程特征。
