Department of Translational Medicine, Università degli Studi del Piemonte Orientale, Novara, Italy.
Department of Translational Medicine, Università degli Studi del Piemonte Orientale, Novara, Italy
BMJ Open. 2023 Jun 19;13(6):e070820. doi: 10.1136/bmjopen-2022-070820.
To find a definition of chronic disease based on literature review and to estimate the population-based prevalence rate of chronicity in a province in Northern Italy.
Retrospective observational study based on administrative databases.
DATA SOURCES/SETTING: Archives of the National Health Service that contain demographic and administrative information linked with the archives of ticket exemptions (2000-2019), the hospital discharge and drug prescriptions (2016-2019).
Subjects who lived in Vercelli Local Health Authority, a Northern Italian province (Piedmont region), and were alive in December 2019.
Prevalence of subjects with at least one chronic disease identified by administrative sources and stratification of population according to the number of comorbidities. The pathologies considered were: chronic ischaemic heart disease, congestive heart failure, cardiac arrhythmias, hypertension, stroke, neoplasm, asthma, chronic obstructive pulmonary disease, diabetes, thyroid disorders, osteoporosis, rheumatoid arthritis, chronic kidney disease, dementia, autism spectrum disorder, depression, schizophrenia, hepatitis, HIV and substance use disorders.
Our target population was about 164 344 subjects. The overall prevalence of subjects with at least one chronic condition was 21.43% (n=35 212): 19 541 were female and 15 671 were male with a raw prevalence of 22.96% and 19.77%, respectively. The overall prevalence increases with age until 85 years old, then a decrease is observed. Moreover, 16.39% had only one pathology, 4.30% two diseases and 0.74% had a more complex clinical condition (more than three diseases).
Despite the difficulty of having a unique definition of chronic disease, the prevalence obtained was coherent with the estimates reported by other national surveillance systems such as Passi and Passi d'Argento. Underestimates were observed when international comparisons were done; however, when we used less stringent definitions of chronic diseases, similar results were obtained.
通过文献回顾寻找慢性病的定义，并估计意大利北部一个省的慢性病人群患病率。
基于行政数据库的回顾性观察研究。
数据来源/设置：国家卫生服务档案，包含与豁免票档案（2000-2019 年）、医院出院和药物处方（2016-2019 年）相关的人口统计和行政信息。
居住在意大利北部皮埃蒙特地区韦尔切利地方卫生局且 2019 年 12 月仍在世的对象。
通过行政来源确定的至少有一种慢性病的患者的患病率，并根据共病数量对人群进行分层。考虑的疾病包括：慢性缺血性心脏病、充血性心力衰竭、心律失常、高血压、中风、肿瘤、哮喘、慢性阻塞性肺疾病、糖尿病、甲状腺疾病、骨质疏松症、类风湿关节炎、慢性肾脏病、痴呆、自闭症谱系障碍、抑郁症、精神分裂症、肝炎、艾滋病和物质使用障碍。
我们的目标人群约为 164344 人。至少有一种慢性疾病的患者总体患病率为 21.43%（n=35212）：女性 19541 人，男性 15671 人，原始患病率分别为 22.96%和 19.77%。总体患病率随年龄增长至 85 岁时达到峰值，然后下降。此外，16.39%的患者仅有一种疾病，4.30%的患者有两种疾病，0.74%的患者有更复杂的临床情况（三种以上疾病）。
尽管慢性病的定义存在困难，但获得的患病率与其他国家监测系统（如 Passi 和 Passi d'Argento）报告的估计值一致。当进行国际比较时，观察到了低估；然而，当我们使用更严格的慢性病定义时，得到了类似的结果。
