Foster H M, Narasimhachari N
J Clin Psychiatry. 1986 Aug;47(8):428-9.
A previously healthy 30-year-old black woman with no history of substance abuse was hospitalized after she attempted to drown her 4-year-old son. She had become progressively confused and delusional after a flu-like illness 2 weeks before. Serum and lumbar CSF samples assayed for phencyclidine (PCP) by gas chromatography-mass spectrometry with d5 PCP as an internal standard were positive. The patient recovered rapidly after treatment with haloperidol and acidification of her urine. Suspicion of PCP abuse should remain high among patients with psychosis, even for those with no history of substance abuse.
一名30岁既往健康、无药物滥用史的黑人女性，在试图溺死其4岁儿子后住院。两周前她患了类似流感的疾病后，逐渐出现意识模糊和妄想症状。血清和腰椎脑脊液样本以d5苯环己哌啶作为内标，采用气相色谱-质谱法检测苯环己哌啶（PCP），结果呈阳性。该患者在接受氟哌啶醇治疗和尿液酸化后迅速康复。对于患有精神病的患者，即使是那些无药物滥用史的患者，也应高度怀疑存在PCP滥用情况。
