Kanji Alpa, Carton James, Hewitt Caroline, Phillips Derrick
Dermatology, Imperial College Healthcare NHS (National Health Service) Trust, London, GBR.
Histopathology, Imperial College Healthcare NHS (National Health Service) Trust, London, GBR.
Cureus. 2023 May 19;15(5):e39231. doi: 10.7759/cureus.39231. eCollection 2023 May.
CD34-positive dermal fibromas (PDFs) are cutaneous neoplasms that display a characteristic pattern of superficial dermal spindle cell proliferation on histopathology evaluation. They are clinically heterogenous in presentation and thought to follow a benign course. CD34-PDFs have features that overlap with dermatofibrosarcoma protuberans (DFSP), a locally aggressive low-grade superficial sarcoma. Cytogenetic studies are essential to distinguish the two. This report presents the case of a 38-year-old female with a CD34-PDF on the right antecubital fossa.
CD34阳性皮肤纤维瘤(PDFs)是一种皮肤肿瘤,在组织病理学评估中显示出特征性的浅表真皮梭形细胞增殖模式。它们在临床表现上具有异质性,被认为病程呈良性。CD34阳性皮肤纤维瘤具有与隆突性皮肤纤维肉瘤(DFSP)重叠的特征,隆突性皮肤纤维肉瘤是一种局部侵袭性的低度浅表肉瘤。细胞遗传学研究对于区分这两者至关重要。本报告介绍了一名38岁女性右侧肘前窝出现CD34阳性皮肤纤维瘤的病例。