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血管腔内修复术后感染性腹主动脉支架移植物的移植物重建临床结局:单中心经验

Clinical outcomes of graft reconstruction in treating infected abdominal aortic stent grafts following endovascular aortic aneurysm repair: a single-center experience.

作者信息

Lee Sang Ah, Jeong Seon Jeong, Gwon Jun Gyo, Han Youngjin, Cho Yong-Pil, Kwon Tae-Won

机构信息

Division of Vascular Surgery, Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

Department of Acute Care Surgery, Korea University Guro Hospital, Seoul, Korea.

出版信息

Ann Surg Treat Res. 2023 Jun;104(6):339-347. doi: 10.4174/astr.2023.104.6.339. Epub 2023 Jun 7.

Abstract

PURPOSE

This study aimed to review our experience with the explantation of infected endovascular aneurysm repair (EVAR) grafts.

METHODS

This single-center, retrospective, observational study analyzed the data of 12 consecutive patients who underwent infected aortic stent graft explantation following EVAR between January 1, 2010 and December 31, 2019, of which 11 underwent graft reconstruction following graft removal. The presentation symptoms, infection route, original pathology of abdominal aortic aneurysms (AAA), graft materials, and clinical outcomes were analyzed.

RESULTS

Six patients underwent total explantation, whereas 5 underwent removal of only the fabric portions. For reconstructions, prosthetic grafts and banked allografts were used in 8 and 3 patients, respectively. Four mechanisms of graft infection were noted in 11 patients: 4 had bacteremia from systemic infections, 3 had persistent infections following EVAR of primary infected AAA, 3 had ascending infections from adjacent abscesses, and 1 had an aneurysm sac erosion resulting in an aortoenteric fistula. No infection-related postoperative complications or reinfections occurred during the mean 65.27-month (standard deviation, ±52.51) follow-up period. One patient died postoperatively because of the rupture of the proximal aortic wall pseudoaneurysm that had occurred during forceful bare stent removal.

CONCLUSION

Regardless of graft material, graft reconstruction is safe for interposition in treating an infected aortic stent graft following EVAR. In our experience, the residual bare stent is no longer a risk factor for reinfection. Therefore, it is important not to injure the proximal aortic wall when removing the bare stent by force.

摘要

目的

本研究旨在回顾我们对感染性血管内动脉瘤修复(EVAR)移植物取出术的经验。

方法

这项单中心、回顾性、观察性研究分析了2010年1月1日至2019年12月31日期间连续12例接受EVAR术后感染性主动脉支架移植物取出术患者的数据,其中11例在移植物移除后进行了移植物重建。分析了患者的临床表现、感染途径、腹主动脉瘤(AAA)的原始病理、移植物材料和临床结果。

结果

6例患者进行了完全取出,而5例仅取出了织物部分。在重建手术中,8例和3例患者分别使用了人工血管移植物和库存同种异体移植物。11例患者中发现了4种移植物感染机制:4例因全身感染出现菌血症,3例在原发性感染性AAA的EVAR术后出现持续性感染,3例因相邻脓肿出现上行性感染,1例因动脉瘤囊侵蚀导致主动脉肠瘘。在平均65.27个月(标准差,±52.51)的随访期内,未发生与感染相关的术后并发症或再感染。1例患者术后因强力取出裸支架时发生近端主动脉壁假性动脉瘤破裂死亡。

结论

无论移植物材料如何,移植物重建用于治疗EVAR术后感染性主动脉支架移植物是安全的。根据我们的经验,残留的裸支架不再是再感染的危险因素。因此,在强力取出裸支架时,避免损伤近端主动脉壁非常重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27c9/10277176/6df643ee5228/astr-104-339-g001.jpg

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