Liu Han, Wu Yechun, Liu Lingli, Yu Jin-Tao, Pan Changduo
School of Petrochemical Engineering, Changzhou University, Changzhou 213164, P. R. China.
School of Chemistry and Chemical Engineering, Jiangsu University of Technology, Changzhou 213001, P. R. China.
Chem Commun (Camb). 2023 Jul 6;59(55):8556-8559. doi: 10.1039/d3cc01908j.
A decarboxylative alkylation of enamides with alkyl diacyl peroxides induced by visible-light is described. The chemo-, regio- and stereoselective olefinic β-C-H alkylation generates a series of primary- and secondary alkylated enamides in yields up to 95%. This transformation bears the advantages of operational simplicity, good functional group compatibility and mild conditions.
本文描述了可见光诱导的烯酰胺与烷基二酰基过氧化物的脱羧烷基化反应。该化学、区域和立体选择性的烯烃β-C-H烷基化反应能生成一系列伯烷基化和仲烷基化的烯酰胺，产率高达95%。这种转化具有操作简单、官能团兼容性好和条件温和的优点。
