Department of Orthopaedics, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health.
Department of Anesthesiology, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China.
J Pediatr Orthop B. 2024 May 1;33(3):258-264. doi: 10.1097/BPB.0000000000001105. Epub 2023 Jun 20.
Increasing evidence demonstrates the advantages of an enhanced recovery after surgery (ERAS) protocol; however, few studies have evaluated ERAS in pediatric patients. This study aimed to evaluate the effect of ERAS in pediatric patients with congenital scoliosis. Seventy pediatric patients with congenital scoliosis underwent posterior hemivertebra resection and fusion with pedicle screws and were prospectively randomly assigned to the ERAS group ( n = 35) and control group ( n = 35). ERAS management comprised 15 elements including a shortened fasting time, optimized anesthesia protocol, and multimodal analgesia. The control group received traditional perioperative management. Clinical outcome was evaluated by hospital stay, surgery-related indicators, diet, pain scores, laboratory tests, and complications. The surgical outcome showed a similar correction rate in the ERAS group (84.0%) and control group (89.0%; P = 0.471). The mean fasting time was significantly shorter in the ERAS group than in the control group. Compared with the control group, the ERAS group had significantly shorter mean times to postoperative hospital stay, first anal exhaust and defecation, significantly lower mean pain scores in the first 2 days postoperatively ( P < 0.05), and a significantly lower mean interleukin-6 concentration on postoperative day 1 ( P < 0.001). The incidence of complications was similar in the ERAS group and control group ( P > 0.05). The ERAS protocol is effective and safe for pediatric patients with congenital spinal deformity and may significantly improve the treatment efficacy compared with traditional perioperative management methods. Levels of Evidence: III.
越来越多的证据表明,术后加速康复(ERAS)方案具有优势;然而,很少有研究评估 ERAS 在儿科患者中的应用。本研究旨在评估 ERAS 在小儿先天性脊柱侧凸患者中的效果。70 例接受后路半椎体切除和椎弓根螺钉融合的小儿先天性脊柱侧凸患者前瞻性随机分为 ERAS 组(n =35)和对照组(n =35)。ERAS 管理包括 15 个要素,包括缩短禁食时间、优化麻醉方案和多模式镇痛。对照组接受传统围手术期管理。通过住院时间、手术相关指标、饮食、疼痛评分、实验室检查和并发症评估临床结果。手术结果显示,ERAS 组(84.0%)和对照组(89.0%;P =0.471)的矫正率相似。ERAS 组的平均禁食时间明显短于对照组。与对照组相比,ERAS 组术后住院时间、首次肛门排气和排便时间、术后前 2 天平均疼痛评分明显缩短(P <0.05),术后第 1 天白细胞介素-6 浓度明显降低(P <0.001)。ERAS 组和对照组的并发症发生率相似(P >0.05)。ERAS 方案对小儿先天性脊柱畸形患者有效且安全,与传统围手术期管理方法相比,可能显著改善治疗效果。证据等级:III。