Neonatology, Max Super Speciality Hospital Shalimar Bagh, New Delhi, Delhi, India.
Neonatology, Max Super Speciality Hospital Shalimar Bagh, New Delhi, Delhi, India
BMJ Case Rep. 2023 Jun 20;16(6):e254187. doi: 10.1136/bcr-2022-254187.
Symptomatic aortic thrombosis is a devastating condition in the neonatal intensive care unit (NICU), which is now increasingly being diagnosed with the availability of bedside ultrasound. Early intervention can go a long way towards preventing adverse outcomes. In our case, a preterm, very low birth weight, growth-restricted baby developed aortic thrombosis with hypertensive emergency and later limb-threatening ischaemia, which usually requires thrombolysis. However, due to the parents' reservations, he was given only therapeutic anticoagulation (with closely monitored activated partial thromboplastin time targets), which resulted in complete thrombus resolution. A multidisciplinary team approach was followed, and early detection with frequent monitoring led us to a favourable outcome.
新生儿重症监护病房（NICU）中出现症状性主动脉血栓是一种灾难性的情况，而现在随着床边超声技术的普及，这种情况的诊断率也越来越高。早期干预可以在很大程度上预防不良结局。在我们的病例中，一个早产儿、极低出生体重、生长受限的婴儿发生了主动脉血栓形成，并伴有高血压危象，随后出现了危及肢体的缺血，通常需要溶栓治疗。然而，由于父母的保留意见，仅对该婴儿进行了治疗性抗凝治疗（密切监测激活部分凝血活酶时间目标），结果血栓完全溶解。我们采取了多学科团队的方法，通过频繁监测进行早期发现，最终取得了良好的结果。
