Department of Surgery, International University of Health and Welfare Hospital, 537-3, Iguchi, Nasushiobara City, Tochigi, 329-2763, Japan.
Center for Photodynamic Medicine, Kochi University, Kohasu Oko-Cho 185-1, Nankoku, Kochi, 783-8505, Japan.
World J Surg. 2023 Oct;47(10):2386-2391. doi: 10.1007/s00268-023-07082-6. Epub 2023 Jun 20.
The conventional near-infrared fluorescent clip (NIRFC) ZEOCLIP FS® has been used successfully in marking tumour sites during laparoscopic surgeries. However, this clip is difficult to observe with the Firefly imaging system equipped with the da Vinci® surgical system. We have been involved in the modification of ZEOCLIP FS® and development of da Vinci-compatible NIRFC. This is the first prospective single-centre case series study verifying the usefulness and safety of the da Vinci-compatible NIRFC.
Twenty-eight consecutive patients undergoing da Vinci®-assisted surgery for gastrointestinal cancer (16 gastric, 4 oesophageal, and 8 rectal cases) between May 2021 and May 2022 were enrolled.
Tumour location was identified by the da Vinci-compatible NIRFCs in 21 of 28 (75%) patients, which involved 12 gastric (75%), 4 oesophageal (100%), and 5 rectal (62%) cancer cases. No adverse events were observed.
Tumour site marking with da Vinci-compatible NIRFC was feasible in 28 patients enrolled in this study. Further studies are warranted to substantiate the safety and improve the recognition rate.
传统的近红外荧光夹（NIRFC）ZEOCLIP FS®已成功用于腹腔镜手术中标记肿瘤部位。然而，这种夹子很难用配备达芬奇®手术系统的 Firefly 成像系统观察到。我们参与了 ZEOCLIP FS®的修改和达芬奇兼容的 NIRFC 的开发。这是第一项验证达芬奇兼容的 NIRFC 的有用性和安全性的前瞻性单中心病例系列研究。
2021 年 5 月至 2022 年 5 月期间，连续 28 例接受达芬奇®辅助胃肠道癌症手术的患者（16 例胃癌、4 例食管癌和 8 例直肠癌）入组。
28 例患者中有 21 例（75%）通过达芬奇兼容的 NIRFC 确定了肿瘤位置，其中包括 12 例胃癌（75%）、4 例食管癌（100%）和 5 例直肠癌（62%）。未观察到不良事件。
在本研究中，28 名入组患者的肿瘤部位标记是可行的。需要进一步的研究来证实安全性并提高识别率。
