[3型固有淋巴细胞（ILC3）在免疫系统进化中的作用：最新进展]
[The role of group 3 innate lymphoid cells(ILC3) in the evolution of the immune system: An update].
作者信息
Xian Yin, Lyu Xiaodong, Cheng Junming, He Ming, Dai Zhengnan, Ren Yixing
机构信息
Hepato-Biliary-Pancreas and Intestinal Disease, Affiliated Hospital of North Sichuan Medical College, Nanchong 637000, China.
Hepato-Biliary-Pancreas and Intestinal Disease, Affiliated Hospital of North Sichuan Medical College, Nanchong 637000, China. *Corresponding author, E-mail:
出版信息
Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2023 Jun;39(6):558-563.
Group 3 innate lymphoid cells (ILC3) are an ILC subset that is characterized by the expression of retinoic acid-related orphan nuclear receptor γt (RORγt) and interleukin 22 (IL-22). This review summarizes the role of ILC3 in coordinating innate immunity and adaptive immunity based on current research and elaborate the significance of ILC3 from the perspective of immune system evolution. In addition, based on immune-related functions, we propose a possible time when ILC3 appears in the evolution of the immune system. And then, the research limitations and prospects are discussed.
第3组固有淋巴细胞（ILC3）是固有淋巴细胞的一个亚群，其特征在于视黄酸相关孤儿核受体γt（RORγt）和白细胞介素22（IL-22）的表达。本综述基于当前研究总结了ILC3在协调固有免疫和适应性免疫中的作用，并从免疫系统进化的角度阐述了ILC3的意义。此外，基于免疫相关功能，我们提出了ILC3在免疫系统进化中可能出现的时间。然后，讨论了研究的局限性和前景。
Zotero 插件