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肠病变在炎症性肠病中的作用:磁共振肠道成像的作用备受关注。

Colonic involvement in inflammatory bowel diseases: spotlight on the role of magnetic resonance enterography.

机构信息

Department of Biomedical Sciences and Morphological and Functional Imaging, University of Messina, Policlinico "G. Martino" Via Consolare Valeria 1, 98100, Messina, Italy.

Postgraduate School of Diagnostic and Interventional Radiology, University of Milan, Milan, Italy.

出版信息

Jpn J Radiol. 2023 Nov;41(11):1208-1215. doi: 10.1007/s11604-023-01456-5. Epub 2023 Jun 21.

DOI:10.1007/s11604-023-01456-5
PMID:37341870
Abstract

The large bowel can be affected by inflammatory bowel diseases, namely ulcerative colitis and Crohn's disease, with the latter occurring either as a unique localization or in conjunction with simultaneous ileal involvement. The differential diagnosis among these conditions is challenging and relies on clinical symptoms, laboratory tests and endoscopy with biopsy. However, as these features can overlap, a conclusive diagnosis is not always achievable, and the underlying cause remains indeterminate. Currently, endoscopy is the reference standard for colonic assessment, although its invasiveness limits its use and repetition within a short timeframe. Magnetic Resonance Enterography is a non-invasive, radiation-free technique that has been extensively and effectively employed in the intestinal evaluation of patients with Crohn's disease in recent years. Although the main goal of this technique is generally focused on evaluating small bowel loops, it can also provide important information about the large bowel if an adequate fulfillment by the oral contrast medium is achieved. The purpose of this work is, therefore, to put emphasis on the potential role of Magnetic Resonance Enterography in assessing the large bowel. In fact, this imaging modality is capable of providing valuable information for comprehensive staging and follow-up of inflammatory bowel diseases within the large bowel, thus complementing the clinical picture and the endoscopic features in the context of a differential diagnosis.

摘要

大肠可受到炎症性肠病的影响,即溃疡性结肠炎和克罗恩病,后者可单独发生于某一部位,也可与同时发生的回肠受累并存。这些疾病的鉴别诊断具有挑战性,依赖于临床症状、实验室检查和内镜检查及活检。然而,由于这些特征可能会重叠,因此并非总能做出明确的诊断,且潜在病因仍不确定。目前,内镜检查是结肠评估的参考标准,但由于其侵袭性,限制了其在短期内的使用和重复。磁共振肠造影术是一种非侵入性、无辐射的技术,近年来已广泛、有效地应用于克罗恩病患者的肠道评估。虽然该技术的主要目标通常集中在评估小肠环,但如果口服对比剂能充分充盈,也能提供关于大肠的重要信息。因此,本工作旨在强调磁共振肠造影术在评估大肠方面的潜在作用。事实上,这种影像学方法能够为大肠炎症性肠病的全面分期和随访提供有价值的信息,从而在鉴别诊断中补充临床和内镜特征。

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本文引用的文献

1
Overview of the Large Bowel Assessment using Magnetic Resonance Imaging: Different Techniques for Current and Emerging Clinical Applications.使用磁共振成像进行大肠评估概述:当前及新兴临床应用的不同技术
Curr Med Imaging. 2022;18(10):1031-1045. doi: 10.2174/1573405618666220331111237.
2
Mimicking conditions of intestinal Crohn's disease: magnetic resonance enterography findings.模拟肠道克罗恩病的条件:磁共振肠造影的发现。
Jpn J Radiol. 2022 Jan;40(1):19-28. doi: 10.1007/s11604-021-01177-7. Epub 2021 Jul 25.
3
Crohn's disease at radiological imaging: focus on techniques and intestinal tract.
克罗恩病的放射影像学表现:聚焦于技术与肠道
Intest Res. 2021 Oct;19(4):365-378. doi: 10.5217/ir.2020.00097. Epub 2020 Nov 25.
4
Should We Divide Crohn's Disease Into Ileum-Dominant and Isolated Colonic Diseases?我们应该将克罗恩病分为以回肠为主型和孤立性结肠疾病吗?
Clin Gastroenterol Hepatol. 2019 Dec;17(13):2634-2643. doi: 10.1016/j.cgh.2019.04.040. Epub 2019 Apr 19.
5
Colonic Crohn's Disease Is Associated with Less Aggressive Disease Course Than Ileal or Ileocolonic Disease.结肠型克罗恩病的疾病进程较回肠型或回结肠型轻。
Dig Dis Sci. 2018 Jun;63(6):1592-1599. doi: 10.1007/s10620-018-5041-4. Epub 2018 Apr 2.
6
Development and Validation of Diagnostic Criteria for IBD Subtypes Including IBD-unclassified in Children: a Multicentre Study From the Pediatric IBD Porto Group of ESPGHAN.儿童炎症性肠病(IBD)亚型包括未分类IBD的诊断标准的制定与验证:欧洲儿科胃肠病、肝病和营养学会(ESPGHAN)儿科IBD波尔图组的多中心研究
J Crohns Colitis. 2017 Sep 1;11(9):1078-1084. doi: 10.1093/ecco-jcc/jjx053.
7
Colonic inflammation in pediatric inflammatory bowel disease: detection with magnetic resonance enterography.儿童炎症性肠病中的结肠炎症:磁共振肠造影检测
Pediatr Radiol. 2017 Jun;47(7):850-859. doi: 10.1007/s00247-017-3833-x. Epub 2017 Apr 17.
8
MR Enterography of Inflammatory Bowel Disease with Endoscopic Correlation.炎症性肠病的磁共振肠造影与内镜对照
Radiographics. 2017 Jan-Feb;37(1):116-131. doi: 10.1148/rg.2017160064. Epub 2016 Nov 25.
9
Recent advances in clinical practice: a systematic review of isolated colonic Crohn's disease: the third IBD?临床实践新进展:孤立性结肠克罗恩病的系统评价:是第三种 IBD 吗?
Gut. 2017 Feb;66(2):362-381. doi: 10.1136/gutjnl-2016-312673. Epub 2016 Oct 6.
10
Crohn's Disease of the Colon, Rectum, and Anus.结肠、直肠和肛门的克罗恩病
Surg Clin North Am. 2015 Dec;95(6):1195-210, vi. doi: 10.1016/j.suc.2015.07.005. Epub 2015 Oct 21.