Cusmano F, Savazzi G M
J Comput Assist Tomogr. 1986 Jul-Aug;10(4):567-70. doi: 10.1097/00004728-198607000-00003.
Sixty-nine uremic patients, 19 on conservative and 50 on regular hemodialysis treatment (RDT), showing no clinical symptoms attributable to central nervous system impairment, were examined by cerebral CT to discover morphological modifications in brain structure and determine their incidence. A CT picture indicative of cortical atrophy was observed in 56.5% of the cases, associated with ventricular atrophy (15.9%), especially in patients on long-term RDT. In addition, CT revealed areas of low density related to past episodes of cerebral ischemia in 10.1% of the cases and some small calcifications in the brain parenchyma in 4.5% of the patients. The degree of these lesions seems to correlate with the duration of uremia.
69例尿毒症患者，其中19例接受保守治疗，50例接受常规血液透析治疗（RDT），均无中枢神经系统损害的临床症状，通过脑部CT检查以发现脑结构的形态学改变并确定其发生率。在56.5%的病例中观察到提示皮质萎缩的CT图像，伴有脑室萎缩（15.9%），尤其在长期接受RDT治疗的患者中。此外，CT显示10.1%的病例存在与既往脑缺血发作相关的低密度区域，4.5%的患者脑实质有一些小钙化。这些病变的程度似乎与尿毒症的病程相关。
