Sakai Akihiro, Ebisumoto Koji, Iijima Hiroaki, Yamauchi Mayu, Teramura Takanobu, Yamazaki Aritomo, Watanabe Takane, Inagi Toshihide, Maki Daisuke, Okami Kenji
Department of Otolaryngology, Head and Neck Surgery Tokai University, School of Medicine Isehara Japan.
Laryngoscope Investig Otolaryngol. 2023 Apr 26;8(3):667-674. doi: 10.1002/lio2.1068. eCollection 2023 Jun.
Transoral salvage surgery has the potential to preserve a patient's quality of life. Therefore, we investigated the outcomes, safety, and risk factors for postoperative complications of salvage transoral videolaryngoscopic surgery (TOVS) for recurrent hypopharyngeal carcinoma after radiotherapy (RT) or chemoradiotherapy (CRT).
This retrospective analysis enrolled patients with hypopharyngeal cancer who had a history of RT or CRT and underwent TOVS from January 2008 to June 2021. The factors related to postoperative complications, postoperative swallowing functions and survival rates were analyzed.
Seven patients (36.8%) of the 19 patients developed complications. Severe dysphagia was the primary complication, and post-cricoid resection was a complication risk factor. The FOSS score was significantly lower in the salvage treatment group. The survival rates were: 3-year overall survival: 94.4%; disease-specific survival: 94.4%; 5-year overall survival: 62.3%; and disease-specific survival: 86.6%.
Salvage TOVS for hypopharyngeal cancer was feasible, and oncologically and functionally reasonable. 2b.
经口挽救性手术有可能保留患者的生活质量。因此，我们调查了放疗（RT）或放化疗（CRT）后复发性下咽癌挽救性经口视频喉镜手术（TOVS）的术后结果、安全性及术后并发症的危险因素。
本回顾性分析纳入了2008年1月至2021年6月期间有RT或CRT病史并接受TOVS的下咽癌患者。分析了与术后并发症、术后吞咽功能和生存率相关的因素。
19例患者中有7例（36.8%）发生并发症。严重吞咽困难是主要并发症，环状软骨后切除术是并发症的危险因素。挽救治疗组的FOSS评分显著更低。生存率为：3年总生存率：94.4%；疾病特异性生存率：94.4%；5年总生存率：62.3%；疾病特异性生存率：86.6%。
下咽癌挽救性TOVS是可行的，在肿瘤学和功能方面是合理的。2b。
