Lieto Eva, Auricchio Annamaria, Belfiore Maria Paola, Del Sorbo Giovanni, De Sena Gabriele, Napolitano Vincenzo, Ruggiero Alessio, Galizia Gennaro, Cardella Francesca
Department of Translational Medical Sciences, University of Campania L. Vanvitelli, Napoli 80138, Campania, Italy.
Department of Precision Medicine, University of Campania L. Vanvitelli, Napoli 80138, Campania, Italy.
World J Gastrointest Surg. 2023 May 27;15(5):972-977. doi: 10.4240/wjgs.v15.i5.972.
Mallory-Weiss syndrome (MWS), representing a linear mucosal laceration at the gastroesophageal junction, is a quite frequent cause of upper gastrointestinal bleeding, usually induced by habitual vomiting. The subsequent cardiac ulceration in this condition is likely due to the concomitance of increased intragastric pressure and inappropriate closure of the gastroesophageal sphincter, collectively inducing ischemic mucosal damage. Usually, MWS is associated with all vomiting conditions, but it has also been described as a complication of prolonged endoscopic procedures or ingested foreign bodies.
We described herein a case of upper gastrointestinal bleeding in a 16-year-old girl with MWS and chronic psychiatric distress, the latter of which deteriorated following her parents' divorce. The patient, who was residing on a small island during the coronavirus disease 2019 pandemic lockdown period, presented with a 2-mo history of habitual vomiting, hematemesis, and a slight depressive mood. Ultimately, a huge intragastric obstructive trichobezoar was detected and discovered to be due to a hidden habit of continuously eating her own hair; this habit had persisted for the past 5 years until a drastic reduction in food intake and corresponding weight loss occurred. The relative isolation in her living status without school attendance had worsened her compulsory habit. The hair agglomeration had reached such enormous dimensions and its firmness was so hard that its potential for endoscopic treatment was judged to be impossible. The patient underwent surgical intervention instead, which culminated in complete removal of the mass.
According to our knowledge, this is the first-ever described case of MWS due to an excessively large trichobezoar.
马洛里-魏斯综合征(MWS)表现为胃食管交界处的线性黏膜撕裂,是上消化道出血的常见原因,通常由习惯性呕吐引起。在此情况下随后发生的贲门溃疡可能是由于胃内压力增加和胃食管括约肌关闭不当共同作用,导致黏膜缺血性损伤。通常,MWS与所有呕吐情况相关,但也被描述为长时间内镜检查或摄入异物的并发症。
我们在此描述了一名16岁患有MWS和慢性精神困扰的女孩发生上消化道出血的病例,后者在其父母离婚后恶化。该患者在2019年冠状病毒病大流行封锁期间居住在一个小岛上,有2个月的习惯性呕吐、呕血病史,并有轻微抑郁情绪。最终,检测到一个巨大的胃内阻塞性毛石,发现是由于持续吃自己头发的隐藏习惯所致;这种习惯在过去5年一直存在,直到食物摄入量大幅减少和相应体重减轻。她因不上学而相对孤立的生活状态使她的强迫性习惯恶化。毛发聚集体已达到如此巨大的尺寸,其硬度如此之硬,以至于判断其无法进行内镜治疗。该患者改为接受手术干预,最终成功完全切除肿块。
据我们所知,这是首例因过大毛石导致MWS的病例。