The Engineering Technological Center of Mushroom Industry, School of Biological Science and Biotechnology, Minnan Normal University, Zhangzhou 363000, PR China.
The Engineering Technological Center of Mushroom Industry, School of Biological Science and Biotechnology, Minnan Normal University, Zhangzhou 363000, PR China.
Int J Biol Macromol. 2023 Jul 31;244:125483. doi: 10.1016/j.ijbiomac.2023.125483. Epub 2023 Jun 19.
Pickering emulsion gels represent a novel class of non-toxic and biocompatible emulsions, offering extensive applications in the pharmaceutical and food additive sectors. This study delineates the synthesis of Pickering emulsion gels utilizing native and amidated pectin samples. Phenylalanine amidated pectin (AP) was procured via an ultra-low temperature enzyme method, while the control group (LP) adhered to an identical procedure without papain catalysis. Experimental outcomes revealed that the AP Pickering emulsion gel manifested superior stability compared to pectin emulsion samples (PE and LP). The Pickering emulsion gel from 5 % amidated pectin (5AP) retained stability throughout a 14-day emulsion stability assessment. Furthermore, all emulsion samples were evaluated for their capacity to deliver and sustain curcumin within an in vitro digestion simulation. Rheological properties and oil droplet size results indicated that the 5AP Pickering emulsion gel exhibited optimal cream index and emulsion stability, effectively inhibiting premature water-oil stratification within the emulsion and augmenting curcumin bioaccessibility. Within the in vitro digestion simulation, the 5AP Pickering emulsion gel demonstrated the highest curcumin bioaccessibility, measured at 17.96 %.
Pickering 乳液凝胶代表了一类新型的无毒且生物相容的乳液,在制药和食品添加剂领域有广泛的应用。本研究利用天然和酰胺化果胶样品合成了 Pickering 乳液凝胶。苯丙氨酸酰胺化果胶(AP)通过超低温酶法获得,而对照组(LP)则遵循相同的程序,没有木瓜蛋白酶的催化。实验结果表明,与果胶乳液样品(PE 和 LP)相比,AP Pickering 乳液凝胶表现出更好的稳定性。5%酰胺化果胶(5AP)的 Pickering 乳液凝胶在 14 天的乳液稳定性评估中保持稳定。此外,所有乳液样品都在体外消化模拟中评估了其递送和维持姜黄素的能力。流变学性质和油滴大小结果表明,5AP Pickering 乳液凝胶表现出最佳的奶油指数和乳液稳定性,有效抑制了乳液中过早的油水分层,并提高了姜黄素的生物利用度。在体外消化模拟中,5AP Pickering 乳液凝胶表现出最高的姜黄素生物利用度,为 17.96%。