State Key Laboratory of Trauma, Burns and Combined Injury, Daping Hospital, Army Medical University, Chongqing, 400042, China; College of Pharmacy and Bioengineering, Chongqing University of Technology, Chongqing, 400054, China.
College of Pharmacy and Bioengineering, Chongqing University of Technology, Chongqing, 400054, China.
J Therm Biol. 2023 May;114:103570. doi: 10.1016/j.jtherbio.2023.103570. Epub 2023 Apr 27.
With the outbreak of the Ukrainian crisis, extremely cold environment warfare has once again become the focus of international attention. People exposed to extremely cold environments may suffer from cold damage, further aggravate trauma, trigger high disability and mortality rates, and even cause serious sequelae. To declare the effects and mechanisms of the extremely cold environment on the body after trauma, this paper reviews, firstly, physiological reaction of human body in an extremely cold environment. Then, the post-traumatic body response in an extremely cold environment was introduced, and finally, the sequelae of trauma in extremely cold environment was further summarized in the paper. The results indicated that extremely cold environment can cause a series of damage to the body, especially the body after trauma. The extremely cold factor is a double-edged sword, showing a favorable and unfavorable side in different aspects. Moreover, in addition to the trauma suffered by the body, the subsequent sequelae such as cognitive dysfunction, anxiety, depression and even post-traumatic stress disorder may also be induced. The paper summarizes the human body's physiological response in an extremely cold environment, and declares the effects and mechanisms of the extremely cold environment on the body after trauma, which may provide a theoretical basis for effectively improving the level of combat trauma treatment in extremely cold regions.
随着乌克兰危机的爆发，极寒环境作战再次成为国际关注的焦点。暴露在极寒环境中的人们可能会遭受冷损伤，进一步加重创伤，引发高残疾率和死亡率，甚至导致严重的后遗症。为了阐明创伤后极寒环境对机体的影响和作用机制，本文首先综述了人体在极寒环境中的生理反应。然后介绍了极寒环境下创伤后的机体反应，最后进一步总结了极寒环境下创伤的后遗症。结果表明，极寒环境会对机体造成一系列损伤，尤其是创伤后的机体。极寒因素是一把双刃剑，在不同方面表现出有利和不利的一面。此外，除了身体受到的创伤外，还可能引发认知功能障碍、焦虑、抑郁甚至创伤后应激障碍等后续后遗症。本文总结了人体在极寒环境中的生理反应，并阐明了极寒环境对创伤后机体的影响和作用机制，这可能为有效提高极寒地区战创伤治疗水平提供理论依据。
