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应用脱细胞真皮基质移植矫正唇裂鼻畸形鼻尖伴开放式鼻整形术

Secondary correction of nasal deformities in cleft lip patients using acellular dermal matrix grafting on the nasal tip with open rhinoplasty.

机构信息

Department of Oral and Maxillofacial Surgery, Affiliated Stomatology Hospital of Guangzhou Medical University, Guangzhou Key Laboratory of Basic and Applied Research of Oral Regenerative Medicine, Guangzhou 510150, China.

Department of Stomatology, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou 510630, China.

出版信息

Br J Oral Maxillofac Surg. 2023 Jul;61(6):416-421. doi: 10.1016/j.bjoms.2023.04.003. Epub 2023 May 9.

DOI:10.1016/j.bjoms.2023.04.003
PMID:37344271
Abstract

Secondary nasal deformities in patients with unilateral cleft lip represent surgical challenges. Open rhinoplasty involving repositioning of the lower lateral cartilage has been shown to be a suitable technique for patients with cleft lip and nose deformities. This study aimed to explore a particular method of rhinoplasty and to assess the aesthetic outcomes for secondary unilateral cleft lip and nose deformities following its use. Fifty-seven patients treated for secondary unilateral cleft lip nasal deformities from January 2012 to December 2018 were enrolled in the study. Open rhinoplasty combined with a reverse-U incision and acellular dermal matrix grafting on the nasal tip was performed in all patients by the same surgeon. In our follow-up study we evaluated the results by measuring angles on photographs and scoring the appearance before and after operation. Data were statistically analysed using the t test. Appearances were improved in all patients. Both the alar base-nasal tip-columellar base angle and the nostril axis angles were smaller postoperatively (p < 0.001). According to the outcome scores, most patients (53/57) agreed that there was an obvious improvement in the appearance of their noses following surgery, and overall they were satisfied with the results of the revision procedure. A distinct improvement in nasal appearance can be achieved with this rhinoplasty. Our surgical method is effective and reliable in patients with secondary unilateral cleft lip and nose deformities, and is worth promoting in the clinic.

摘要

继发于单侧唇裂的鼻部畸形是外科手术的难点。开放式鼻整形术通过重新定位鼻翼软骨,已被证明是治疗唇裂鼻畸形的一种合适技术。本研究旨在探讨一种特殊的鼻整形术方法,并评估其在继发单侧唇裂鼻畸形中的美学效果。

2012 年 1 月至 2018 年 12 月,我们对 57 例继发单侧唇裂鼻畸形患者进行了研究。所有患者均由同一位医生行开放式鼻整形术,术中采用逆行 U 切口和脱细胞真皮基质移植物进行鼻尖整形。在随访研究中,我们通过测量照片上的角度并对手术前后的外观进行评分来评估结果。数据采用 t 检验进行统计学分析。

所有患者的外观均得到改善。术后鼻翼基底-鼻尖-小柱基底角和鼻孔轴角均减小(p<0.001)。根据术后评分,大多数患者(53/57)认为术后鼻部外观明显改善,总体上对修复手术的结果满意。

本研究中采用的这种鼻整形术可显著改善鼻部外观。对于继发单侧唇裂鼻畸形患者,我们的手术方法有效且可靠,值得在临床中推广。

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