Ah-Thiane Loic, Rousseau Caroline, Aumont Maud, Cailleteau Axel, Doré Mélanie, Mervoyer Augustin, Vaugier Loig, Supiot Stéphane
Department of Radiotherapy, ICO René Gauducheau, Boulevard Jacques Monod, 44800 St-Herblain, France.
Department of Nuclear Medicine, ICO René Gauducheau, Boulevard Jacques Monod, 44800 St-Herblain, France.
Cancers (Basel). 2023 May 12;15(10):2736. doi: 10.3390/cancers15102736.
The sentinel lymph node technique is minimally invasive and used routinely by surgeons, reducing the need for morbid extensive lymph node dissections, which is a significant advantage for cancer staging and treatment decisions. The sentinel lymph node could also help radiation oncologists to identify tumor drainage for each of their patients, leading to a more personalized radiotherapy, instead of a probabilistic irradiation based on delineation atlases. The aim is both to avoid recurrence in unexpected areas and to limit the volume of irradiated healthy tissues. The aim of our study is to evaluate the impact of sentinel lymph node mapping for radiation oncologists. This concept, relying on sentinel lymph node mapping for treatment planning, is known as lymph-flow-guided radiotherapy. We present an up-to-date narrative literature review showing the potential applications of the sentinel lymph node technique for radiotherapy, as well as the limits that need to be addressed before its routine usage.
前哨淋巴结技术是微创的，外科医生经常使用，减少了进行病态广泛淋巴结清扫的必要性，这对癌症分期和治疗决策具有显著优势。前哨淋巴结还可以帮助放射肿瘤学家确定每位患者的肿瘤引流情况，从而实现更个性化的放射治疗，而不是基于描绘图谱进行概率性照射。目的是既避免意外区域的复发，又限制受照射健康组织的体积。我们研究的目的是评估前哨淋巴结定位对放射肿瘤学家的影响。这一依赖前哨淋巴结定位进行治疗计划的概念被称为淋巴流引导放疗。我们进行了一项最新的叙述性文献综述，展示了前哨淋巴结技术在放射治疗中的潜在应用，以及在其常规使用之前需要解决的局限性。
