Evbayekha Endurance O, Nwachukwu Elochukwu U, Nikravesh Elham, Rosas Valene, Onuegbu Chinwendu A, Egwuonwu Obinna F, Eguagie Osazee, Chioma Ogochukwu E, Agho Awanwosa V, Samuels Kemar A, Willie Anthony, Nwafor Jane N, Esene-Akhideno Laura N, Adigun Aisha O
Internal Medicine, St. Luke's Hospital, Chesterfield, USA.
Family Medicine, University of Uyo Teaching Hospital, Uyo, NGA.
Cureus. 2023 May 20;15(5):e39261. doi: 10.7759/cureus.39261. eCollection 2023 May.
Berberine (BBR) is an ancient plant popular in China and is used to treat dyslipidemia, among other cardiovascular and metabolic-related diseases. BBR has historically been regarded as having multiple benefits, with a few clinical trials indicating this fact. We searched PubMed, Embase, and Google Scholar with the following keywords: Berberidaceae, berberine, Berberis spp., dyslipidemia, atherosclerosis, and inflammation. We synthesized the information within the literature to provide an updated review of BBR, its potential, and its applicability in real-world medicine in the future. This review sought to evaluate the literature and advancement in BBR's efficacy regarding dyslipidemia, inflammation, and atherosclerosis.
黄连素(BBR)是一种在中国广为人知的古老植物,用于治疗血脂异常以及其他一些心血管和代谢相关疾病。历史上,BBR一直被认为具有多种益处,一些临床试验也表明了这一点。我们使用以下关键词在PubMed、Embase和谷歌学术上进行了搜索:小檗科、黄连素、小檗属、血脂异常、动脉粥样硬化和炎症。我们综合了文献中的信息,以提供对BBR及其潜力以及未来在实际医学中适用性的最新综述。本综述旨在评估BBR在血脂异常、炎症和动脉粥样硬化疗效方面的文献和进展。