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了解特立尼达和多巴哥的肾衰竭负担:对一个区域中心流行病学数据的综述

Understanding the Burden of Kidney Failure in Trinidad and Tobago: A Review of the Epidemiological Data From a Regional Center.

作者信息

Ramrattan Amit, Mohammed Emile P, Bodkin Darren

机构信息

Internal Medicine, Port of Spain General Hospital, Port of Spain, TTO.

Neonatology, UPMC (University of Pittsburgh Medical Center) Children's Hospital of Pittsburgh, Pittsburgh, USA.

出版信息

Cureus. 2023 Jun 19;15(6):e40663. doi: 10.7759/cureus.40663. eCollection 2023 Jun.

DOI:10.7759/cureus.40663
PMID:37347076
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10281740/
Abstract

Objective The aim of this study was to determine the incidence of new patients requiring renal replacement therapy and to gather data on sex, age, ethnicity, mortality, and causes of kidney failure in Trinidad and Tobago in comparison with the rest of the world. Method Electronic data were gathered for new patients initiating dialysis between January 1, 2016, and December 31, 2017, including the date of dialysis initiation, age, gender, ethnicity, diagnosis, dialysis access and modality, and outcome at three months and the end of the year. The data were analyzed using simple descriptive statistics via Microsoft Excel (Microsoft Corporation, Redmond, Washington, United States). Results Over a two-year period, 265 new patients underwent renal replacement therapy, of which 51.7% were 50-69 years of age, 53.9% were male, 46% were female, 67.9% were Afro-Trinidadian, and 38.1% had a combination of diabetes mellitus and hypertension as the cause of kidney failure. The incidence rates of treated end-stage renal disease (ESRD) globally in 2016 and 2017 were 306 and 224 per million population, respectively, and mortality for both years was 32% and 32.1%, respectively. Conclusion Our study showed that Trinidad and Tobago has one of the highest incidences of patients initiating renal replacement therapy and mortality rates.

摘要

目的 本研究旨在确定特立尼达和多巴哥需要肾脏替代治疗的新患者的发病率,并收集有关性别、年龄、种族、死亡率以及肾衰竭病因的数据,以便与世界其他地区进行比较。方法 收集了2016年1月1日至2017年12月31日开始透析的新患者的电子数据,包括透析开始日期、年龄、性别、种族、诊断、透析通路和方式,以及三个月和年底时的结局。通过Microsoft Excel(美国华盛顿州雷德蒙德市微软公司)使用简单描述性统计方法对数据进行分析。结果 在两年期间,265名新患者接受了肾脏替代治疗,其中51.7%的患者年龄在50至69岁之间,53.9%为男性,46%为女性,67.9%为非裔特立尼达人,38.1%的患者肾衰竭病因是糖尿病和高血压合并。2016年和2017年全球接受治疗的终末期肾病(ESRD)发病率分别为每百万人口306例和224例,这两年的死亡率分别为32%和32.1%。结论 我们的研究表明,特立尼达和多巴哥是开始接受肾脏替代治疗的患者发病率和死亡率最高的地区之一。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d097/10281740/a4c02520fe62/cureus-0015-00000040663-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d097/10281740/72dd4a984519/cureus-0015-00000040663-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d097/10281740/dfab7bac25ee/cureus-0015-00000040663-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d097/10281740/c8108a994062/cureus-0015-00000040663-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d097/10281740/31b3cf17aab3/cureus-0015-00000040663-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d097/10281740/a4c02520fe62/cureus-0015-00000040663-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d097/10281740/72dd4a984519/cureus-0015-00000040663-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d097/10281740/dfab7bac25ee/cureus-0015-00000040663-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d097/10281740/c8108a994062/cureus-0015-00000040663-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d097/10281740/31b3cf17aab3/cureus-0015-00000040663-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d097/10281740/a4c02520fe62/cureus-0015-00000040663-i05.jpg

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US Renal Data System 2020 Annual Data Report: Epidemiology of Kidney Disease in the United States.《美国肾脏数据系统2020年年报:美国肾脏疾病流行病学》
Am J Kidney Dis. 2021 Apr;77(4 Suppl 1):A7-A8. doi: 10.1053/j.ajkd.2021.01.002.
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Global Epidemiology of End-Stage Kidney Disease and Disparities in Kidney Replacement Therapy.
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Am J Nephrol. 2021;52(2):98-107. doi: 10.1159/000514550. Epub 2021 Mar 22.
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Worldwide Frequencies of APOL1 Renal Risk Variants.载脂蛋白L1(APOL1)肾脏风险变异的全球频率。
N Engl J Med. 2018 Dec 27;379(26):2571-2572. doi: 10.1056/NEJMc1800748.
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