Sugiyama Tomohiro, Takeuchi Yuji, Kinoshita Osamu, Mori Yoshihiro, Higuchi Ichiro, Tsuchida Yasuaki
Department of Digestive Surgery, Iseikai Hospital, Osaka, Japan.
Department of Digestive Surgery, Iseikai Hospital, Osaka, Japan.
Int J Surg Case Rep. 2023 Jul;108:108401. doi: 10.1016/j.ijscr.2023.108401. Epub 2023 Jun 19.
Collagenous colitis is an inflammatory disease characterized by hyperplasia of the collagen band beneath the colonic mucous membrane. Chronic diarrhea is a characteristic clinical symptom. The disease is often diagnosed accidentally on colonoscopy for chronic diarrhea, and patients without chronic diarrhea have few chances to suspect the disease.
The patient was a 75-year-old woman. The chief complaint was sudden upper abdominal pain and vomiting. There were no important findings regarding the consumed food or bowel habits (no diarrhea). Computed tomography revealed wall thickness and a small amount of free air around the descending colon. An emergency laparotomy was performed with the diagnosis of spontaneous colonic perforation. Intra-operative findings revealed a longitudinal ulcer and micro-perforation to the mesenterial side at the descending colon. Pathological findings revealed subepithelial collagenous band in the submucosal background of the ulcer, and which was diagnosed as collagenous colitis.
Intestinal perforation in collagenous colitis is extremely rare. It was considered that perforation was caused by a transient increase in intestinal pressure in the background of collagenous colitis. Further, to the best of our knowledge, this is the first report of a critical case which presented without the characteristic symptom of chronic diarrhea.
We report a rare case of colonic perforation of the collagenous colitis.
胶原性结肠炎是一种以结肠黏膜下胶原带增生为特征的炎症性疾病。慢性腹泻是其典型的临床症状。该疾病常因慢性腹泻在结肠镜检查时意外被诊断出来,而没有慢性腹泻症状的患者很少会怀疑患有此病。
患者为一名75岁女性。主要症状为突发上腹部疼痛和呕吐。在饮食或排便习惯方面(无腹泻)未发现重要异常。计算机断层扫描显示降结肠壁增厚及少量游离气体。诊断为自发性结肠穿孔后进行了急诊剖腹手术。术中发现降结肠有纵向溃疡及系膜侧微穿孔。病理检查结果显示溃疡黏膜下背景中有上皮下胶原带,诊断为胶原性结肠炎。
胶原性结肠炎并发肠穿孔极为罕见。推测穿孔是在胶原性结肠炎背景下肠内压力短暂升高所致。此外,据我们所知,这是首例无慢性腹泻这一典型症状的重症病例报告。
我们报告了一例罕见的胶原性结肠炎并发结肠穿孔病例。