Reisman S, Maddahi J, Van Train K, Garcia E, Berman D
J Nucl Med. 1986 Aug;27(8):1273-81.
Previous quantitation of exercise-redistribution planar 201TI scintigraphy has shown high sensitivity and specificity in the detection of coronary artery disease and improved detection of individual coronary stenoses over visual analysis. By using similar methodology based on the circumferential profile method, we studied 133 patients to quantitatively assess the extent, depth, and severity of thallium defects compared with consensus visual analysis. These quantitative measurements are objective, requiring only three operator interactions. In comparing quantitative and visual results, a close correlation was found for measurement of extent of thallium defect (r = 0.73) and severity of defect (r = 0.79). In detecting patients with the high-risk scintigraphic pattern of a severe stress thallium defect, a quantitative depth score of greater than or equal to 36 had an 81% sensitivity and an 82% specificity. Thus, this nearly automatic, computerized quantitative method allows objective determination of extent, severity, and depth of planar 201TI defects.
既往对运动-再分布平面201铊闪烁扫描的定量分析显示，其在检测冠状动脉疾病方面具有高敏感性和特异性，并且与视觉分析相比，能更好地检测出单个冠状动脉狭窄。通过使用基于圆周轮廓法的类似方法，我们对133例患者进行了研究，以与一致性视觉分析相比较，定量评估铊缺损的范围、深度和严重程度。这些定量测量是客观的，仅需操作人员进行三次交互操作。在比较定量和视觉结果时，发现铊缺损范围测量（r = 0.73）和缺损严重程度测量（r = 0.79）之间存在密切相关性。在检测具有严重应激铊缺损的高危闪烁扫描模式的患者时，定量深度评分大于或等于36时，敏感性为81%，特异性为82%。因此，这种近乎自动的计算机化定量方法可客观确定平面201铊缺损的范围、严重程度和深度。
