• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

院前环境中儿童哮喘急性发作的治疗:一项回顾性观察研究。

Acute paediatric asthma treatment in the prehospital setting: a retrospective observational study.

机构信息

Paediatric Emergency Department, Monash Medical Centre Clayton, Clayton, Victoria, Australia

Department of Paediatrics, Monash University, Clayton, Victoria, Australia.

出版信息

BMJ Open. 2023 Jun 22;13(6):e073029. doi: 10.1136/bmjopen-2023-073029.

DOI:10.1136/bmjopen-2023-073029
PMID:37349099
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10314617/
Abstract

OBJECTIVES

To describe the incidence of and patterns of 'escalated care' (care in addition to standard treatment with systemic corticosteroids and inhaled bronchodilators) for children receiving prehospital treatment for asthma.

DESIGN

Retrospective observational study.

SETTING

State-wide ambulance service data (Ambulance Victoria in Victoria, Australia, population 6.5 million) PARTICIPANTS: Children aged 1-17 years and given a final diagnosis of asthma by the treating paramedics and/or treated with inhaled bronchodilators from 1 July 2019 to 30 June 2020.

PRIMARY AND SECONDARY OUTCOME MEASURES

We classified 'escalation of care' as parenteral administration of epinephrine, or provision of respiratory support. We compared clinical, demographic and treatments administered between those receiving and not receiving escalation of care.

RESULTS

Paramedics attended 1572 children with acute exacerbations of asthma during the 1 year study period. Of these, 22 (1.4%) had escalated care, all receiving parenteral epinephrine. Patients with escalated care were more likely to be older, had previously required hospital admission for asthma and had severe respiratory distress at initial assessment.Of 1307 children with respiratory status data available, at arrival to hospital, the respiratory status of children had improved overall (normal/mild respiratory distress at initial assessment 847 (64.8%), normal/mild respiratory distress at hospital arrival 1142 (87.4%), p<0.0001).

CONCLUSIONS

Most children with acute exacerbations of asthma did not receive escalated therapy during their pre-hospital treatment from ambulance paramedics. Most patients were treated with inhaled bronchodilators only and clinically improved by the time they arrived in hospital.

摘要

目的

描述接受院前治疗的哮喘儿童接受“升级治疗”(除全身皮质类固醇和吸入性支气管扩张剂标准治疗之外的治疗)的发生率和模式。

设计

回顾性观察性研究。

地点

全州范围的救护车服务数据(澳大利亚维多利亚州的救护车维多利亚,人口 650 万)

参与者

年龄在 1 至 17 岁之间的儿童,由治疗护理人员最终诊断为哮喘,并在 2019 年 7 月 1 日至 2020 年 6 月 30 日期间接受吸入性支气管扩张剂治疗。

主要和次要结果测量

我们将“治疗升级”分为肾上腺素的静脉内给药或提供呼吸支持。我们比较了接受和未接受升级治疗的患者的临床、人口统计学和治疗方法。

结果

在 1 年的研究期间,护理人员共对 1572 名患有急性哮喘发作的儿童进行了治疗。其中 22 名(1.4%)接受了升级治疗,均接受了肾上腺素的静脉内给药。接受升级治疗的患者年龄更大,以前因哮喘需要住院治疗,初始评估时呼吸窘迫严重。在 1307 名有呼吸状况数据的儿童中,在到达医院时,儿童的呼吸状况总体上有所改善(初始评估时正常/轻度呼吸窘迫 847 例(64.8%),到达医院时正常/轻度呼吸窘迫 1142 例(87.4%),p<0.0001)。

结论

大多数患有急性哮喘发作的儿童在接受救护车护理人员的院前治疗期间未接受升级治疗。大多数患者仅接受吸入性支气管扩张剂治疗,到达医院时临床状况有所改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f853/10314617/b16fddcbc4a6/bmjopen-2023-073029f02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f853/10314617/56c426ffa1e3/bmjopen-2023-073029f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f853/10314617/b16fddcbc4a6/bmjopen-2023-073029f02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f853/10314617/56c426ffa1e3/bmjopen-2023-073029f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f853/10314617/b16fddcbc4a6/bmjopen-2023-073029f02.jpg

相似文献

1
Acute paediatric asthma treatment in the prehospital setting: a retrospective observational study.院前环境中儿童哮喘急性发作的治疗:一项回顾性观察研究。
BMJ Open. 2023 Jun 22;13(6):e073029. doi: 10.1136/bmjopen-2023-073029.
2
Interventions for escalation of therapy for acute exacerbations of asthma in children: an overview of Cochrane Reviews.儿童哮喘急性加重期治疗升级的干预措施:Cochrane系统评价综述
Cochrane Database Syst Rev. 2020 Aug 5;8(8):CD012977. doi: 10.1002/14651858.CD012977.pub2.
3
Treatment patterns and frequency of key outcomes in acute severe asthma in children: a Paediatric Research in Emergency Departments International Collaborative (PREDICT) multicentre cohort study.儿童急性重症哮喘的治疗模式和关键结局的发生频率:儿科急诊研究国际协作组织(PREDICT)多中心队列研究。
BMJ Open Respir Res. 2022 Mar;9(1). doi: 10.1136/bmjresp-2021-001137.
4
Prehospital continuous positive airway pressure for acute respiratory failure: the ACUTE feasibility RCT.院前持续气道正压通气治疗急性呼吸衰竭:ACUTE 可行性 RCT。
Health Technol Assess. 2021 Feb;25(7):1-92. doi: 10.3310/hta25070.
5
Prehospital benzodiazepine use and need for respiratory support in paediatric seizures.院前苯二氮䓬类药物的使用与小儿惊厥时呼吸支持的需求。
Emerg Med J. 2022 Aug;39(8):608-615. doi: 10.1136/emermed-2021-211735. Epub 2022 Jan 25.
6
Impact of prehospital pediatric asthma management protocol adherence on clinical outcomes.院前儿童哮喘管理方案依从性对临床结局的影响。
J Asthma. 2022 May;59(5):937-945. doi: 10.1080/02770903.2021.1881969. Epub 2021 Feb 13.
7
Inhaled magnesium sulfate in the treatment of acute asthma.吸入硫酸镁治疗急性哮喘。
Cochrane Database Syst Rev. 2017 Nov 28;11(11):CD003898. doi: 10.1002/14651858.CD003898.pub6.
8
MAGNEsium Trial In Children (MAGNETIC): a randomised, placebo-controlled trial and economic evaluation of nebulised magnesium sulphate in acute severe asthma in children.儿童 MAGNEsium 试验(MAGNETIC):雾化硫酸镁治疗儿童急性重度哮喘的随机、安慰剂对照试验和经济评价。
Health Technol Assess. 2013 Oct;17(45):v-vi, 1-216. doi: 10.3310/hta17450.
9
Early Administration of Steroids in the Ambulance Setting: An Observational Design Trial (EASI-AS-ODT).早期在救护车环境中使用类固醇:一项观察性设计试验(EASI-AS-ODT)。
Acad Emerg Med. 2024 Jan;31(1):49-60. doi: 10.1111/acem.14813. Epub 2023 Oct 19.
10
Emergency pre-hospital management of patients admitted with acute asthma.急性哮喘入院患者的院前急救管理
Thorax. 2000 Feb;55(2):97-101. doi: 10.1136/thorax.55.2.97.

本文引用的文献

1
Treatment patterns and frequency of key outcomes in acute severe asthma in children: a Paediatric Research in Emergency Departments International Collaborative (PREDICT) multicentre cohort study.儿童急性重症哮喘的治疗模式和关键结局的发生频率:儿科急诊研究国际协作组织(PREDICT)多中心队列研究。
BMJ Open Respir Res. 2022 Mar;9(1). doi: 10.1136/bmjresp-2021-001137.
2
Prehospital benzodiazepine use and need for respiratory support in paediatric seizures.院前苯二氮䓬类药物的使用与小儿惊厥时呼吸支持的需求。
Emerg Med J. 2022 Aug;39(8):608-615. doi: 10.1136/emermed-2021-211735. Epub 2022 Jan 25.
3
Improving Administration of Prehospital Corticosteroids for Pediatric Asthma.
改善儿童哮喘院前皮质类固醇的管理
Pediatr Qual Saf. 2021 May 19;6(3):e410. doi: 10.1097/pq9.0000000000000410. eCollection 2021 May-Jun.
4
Impact of prehospital pediatric asthma management protocol adherence on clinical outcomes.院前儿童哮喘管理方案依从性对临床结局的影响。
J Asthma. 2022 May;59(5):937-945. doi: 10.1080/02770903.2021.1881969. Epub 2021 Feb 13.
5
Management of Asthma Exacerbations in the Emergency Department.急诊科哮喘急性发作的管理。
J Allergy Clin Immunol Pract. 2021 Jul;9(7):2599-2610. doi: 10.1016/j.jaip.2020.12.037. Epub 2020 Dec 31.
6
Variability in care for children with severe acute asthma in Latin America.拉丁美洲儿童严重急性哮喘护理的变异性。
Pediatr Pulmonol. 2021 Feb;56(2):384-391. doi: 10.1002/ppul.25212. Epub 2020 Dec 17.
7
High-Flow Nasal Cannula Use Outside of the ICU Setting.高流量鼻导管在 ICU 环境之外的应用。
Pediatrics. 2020 Nov;146(5). doi: 10.1542/peds.2019-4083. Epub 2020 Oct 8.
8
Interventions for escalation of therapy for acute exacerbations of asthma in children: an overview of Cochrane Reviews.儿童哮喘急性加重期治疗升级的干预措施:Cochrane系统评价综述
Cochrane Database Syst Rev. 2020 Aug 5;8(8):CD012977. doi: 10.1002/14651858.CD012977.pub2.
9
Intravenous Magnesium in Asthma Pharmacotherapy: Variability in Use in the PECARN Registry.静脉注射镁在哮喘药物治疗中的应用:PECARN 登记处使用情况的变异性。
J Pediatr. 2020 May;220:165-174.e2. doi: 10.1016/j.jpeds.2020.01.062. Epub 2020 Mar 5.
10
Variability of outcome measures in trials of intravenous therapy in acute severe paediatric asthma: a systematic review.静脉治疗急性重度儿童哮喘试验中结局测量指标的变异性:系统评价。
Emerg Med J. 2019 Apr;36(4):225-230. doi: 10.1136/emermed-2018-207929. Epub 2018 Nov 27.