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小儿肺脓肿通过咳嗽、导管引流或完全切除进行治疗。

Drainage of pediatric lung abscess by cough, catheter, or complete resection.

作者信息

Kosloske A M, Ball W S, Butler C, Musemeche C A

出版信息

J Pediatr Surg. 1986 Jul;21(7):596-600. doi: 10.1016/s0022-3468(86)80413-4.

Abstract

We treated eight children, aged 7 weeks to 17 years, for lung abscess. Each abscess followed an episode of aspiration or a bacterial pneumonia. Associated conditions were leukemia, congenital immune deficiency, endocarditis, cerebral palsy, and prematurity. Seven of the 8 children had polymicrobial infections, usually containing both aerobic and anaerobic bacteria. The success of medical treatment by antibiotics and chest physiotherapy was age related; 3 of the 8 children, aged 10 to 17 years, recovered on this regimen, whereas five children, aged 7 weeks to 7 years, required catheter drainage or resection for cure. Drainage by catheter pneumonostomy was performed for solitary peripheral bacterial abscesses. A large intercostal catheter was inserted into the cavity, either operatively or percutaneously. Wedge resection was performed for multiple, central, or fungal abscesses. Pneumonostomy was curative in 3 of 4 children. One chronic abscess recurred after pneumonostomy and required resection. Wedge resection was curative in the two children who came to thoracotomy; lobectomy was not necessary. Although all eight children recovered from their lung abscesses, three of them died within a year of sepsis. Lung abscess today occurs in immunocompromised children who are vulnerable to fatal infections. Chest physiotherapy is unlikely to achieve good drainage in children under 7 years of age. Medical failures can be identified within the first week of treatment. Early and aggressive surgical treatment is indicated in such children, and may be lifesaving.

摘要

我们治疗了8名年龄在7周至17岁之间的肺脓肿患儿。每个脓肿都继发于一次误吸事件或细菌性肺炎。相关疾病包括白血病、先天性免疫缺陷、心内膜炎、脑瘫和早产。8名儿童中有7名发生了混合菌感染,通常同时含有需氧菌和厌氧菌。抗生素和胸部物理治疗的治疗成功率与年龄有关;8名年龄在10至17岁的儿童中有3名通过该治疗方案康复,而5名年龄在7周至7岁的儿童需要导管引流或手术切除才能治愈。对于孤立的外周细菌性脓肿,采用经皮肺造口导管引流。通过手术或经皮将一根大的肋间导管插入脓腔。对于多发性、中央性或真菌性脓肿,进行楔形切除术。4名儿童中有3名经肺造口术治愈。1例慢性脓肿在肺造口术后复发,需要手术切除。接受开胸手术的两名儿童经楔形切除术治愈;无需进行肺叶切除术。尽管所有8名儿童的肺脓肿均已康复,但其中3名在脓毒症发生后一年内死亡。如今,肺脓肿发生在易发生致命感染的免疫功能低下儿童中。胸部物理治疗在7岁以下儿童中不太可能实现良好的引流。在治疗的第一周内即可识别出治疗失败的情况。对于此类儿童,应尽早进行积极的手术治疗,这可能挽救生命。

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