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急性腐蚀性摄入的紧急外科干预:来自印度的单中心经验。

Emergency surgical intervention in acute corrosive ingestion: single-center experience from India.

机构信息

Department of Surgical Gastroenterology, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.

Department of Gastroenterology, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.

出版信息

ANZ J Surg. 2023 Dec;93(12):2864-2869. doi: 10.1111/ans.18576. Epub 2023 Jun 23.

Abstract

BACKGROUND

Surgical intervention for acute corrosive injury is often required. It is associated with considerable morbidity and mortality. Sparce data is available on the types and timing of surgery after acute corrosive ingestion and complications associated with the same.

METHODS

This is a retrospective single-center study from a tertiary care center in India. All patients who underwent surgical exploration after acute corrosive intake between January 2003 and June 2014 were enrolled in the study. Data on patients' presentation, their endoscopic findings, indications of surgery, type of surgery and post-operative follow-up was retrieved.

RESULTS

Out of 170 patients who presented with acute corrosive ingestion, 24 patients (14.11%) required emergency surgery. The mean interval between ingestion and surgery was 9.92 ± 9.03 days. Presence of peritonitis was the most common indication for surgery (n = 10; 41.7%) followed by mediastinitis (n = 7; 29.2%). A total of 17 resectional and 7 non-resectional procedures were performed. Thirteen (54%) patients succumbed to their illness post-operatively due to multi-organ failure (n = 9), refractory shock (n = 3) or pulmonary thromboembolism (n = 1). Patients with early surgery (≤7 days) after corrosive ingestion had similar mortality compared to patients with late surgery (>7 days) (50% versus 67%; P = 0.30). Of the 11 surviving patients, eight patients (72%) underwent successful reconstructive surgery on follow-up.

CONCLUSIONS

Emergency surgery after corrosive ingestion carries high morbidity and mortality. However, after the initial stormy acute phase, majority of patients can undergo successful reconstructive surgery on follow-up.

摘要

背景

急性腐蚀性损伤常需手术干预,其与较高的发病率和死亡率相关。目前仅有少量数据可用于评估腐蚀性摄入后的手术类型和时机,以及相关并发症。

方法

这是一项来自印度一家三级医疗中心的回顾性单中心研究。研究纳入了 2003 年 1 月至 2014 年 6 月间所有因急性腐蚀性摄入而接受手术探查的患者。检索患者表现、内镜检查结果、手术指征、手术类型和术后随访的数据。

结果

在 170 例急性腐蚀性摄入的患者中,24 例(14.11%)需要紧急手术。摄入与手术之间的平均间隔为 9.92±9.03 天。腹膜炎(n=10;41.7%)是最常见的手术指征,其次是纵隔炎(n=7;29.2%)。共实施了 17 例切除术和 7 例非切除术。13 例(54%)患者术后因多器官衰竭(n=9)、难治性休克(n=3)或肺血栓栓塞症(n=1)死亡。腐蚀性摄入后早期手术(≤7 天)与晚期手术(>7 天)患者的死亡率相似(50%比 67%;P=0.30)。在 11 例存活患者中,8 例(72%)在随访中接受了成功的重建手术。

结论

腐蚀性摄入后的急诊手术并发症发病率和死亡率较高。然而,在初始急性危险期过后,大多数患者可在随访中接受成功的重建手术。

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