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What's new in intensive care: disease tolerance.

作者信息

Powell Rachel E, Soares Miguel P, Weis Sebastian

机构信息

Clinical Research, Investigation, and Systems Modeling of Acute Illness (CRISMA) Center, Pittsburgh, PA, USA.

Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.

出版信息

Intensive Care Med. 2023 Oct;49(10):1235-1237. doi: 10.1007/s00134-023-07130-8. Epub 2023 Jun 23.

DOI:10.1007/s00134-023-07130-8
PMID:37353606
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10556172/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f320/10556172/351b606b2909/134_2023_7130_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f320/10556172/351b606b2909/134_2023_7130_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f320/10556172/351b606b2909/134_2023_7130_Fig1_HTML.jpg

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本文引用的文献

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Combined glucocorticoid resistance and hyperlactatemia contributes to lethal shock in sepsis.糖皮质激素抵抗合并高乳酸血症导致脓毒症致死性休克。
Cell Metab. 2021 Sep 7;33(9):1763-1776.e5. doi: 10.1016/j.cmet.2021.07.002. Epub 2021 Jul 23.
2
TOP1 inhibition therapy protects against SARS-CoV-2-induced lethal inflammation.TOP1 抑制疗法可预防 SARS-CoV-2 引起的致命性炎症。
Cell. 2021 May 13;184(10):2618-2632.e17. doi: 10.1016/j.cell.2021.03.051. Epub 2021 Mar 30.
3
Disease Tolerance as an Inherent Component of Immunity.疾病耐受作为免疫的固有组成部分。
Annu Rev Immunol. 2019 Apr 26;37:405-437. doi: 10.1146/annurev-immunol-042718-041739. Epub 2019 Jan 23.
4
Metabolic Adaptation Establishes Disease Tolerance to Sepsis.代谢适应建立对脓毒症的疾病耐受性。
Cell. 2017 Jun 15;169(7):1263-1275.e14. doi: 10.1016/j.cell.2017.05.031.
5
Tracking Resilience to Infections by Mapping Disease Space.通过绘制疾病空间来追踪对感染的抵抗力
PLoS Biol. 2016 Apr 18;14(4):e1002436. doi: 10.1371/journal.pbio.1002436. eCollection 2016 Apr.
6
Homeostasis, inflammation, and disease susceptibility.体内平衡、炎症与疾病易感性。
Cell. 2015 Feb 26;160(5):816-827. doi: 10.1016/j.cell.2015.02.010.
7
Tissue damage control in disease tolerance.疾病耐受中的组织损伤控制。
Trends Immunol. 2014 Oct;35(10):483-94. doi: 10.1016/j.it.2014.08.001. Epub 2014 Aug 30.
8
Anthracyclines induce DNA damage response-mediated protection against severe sepsis.蒽环类抗生素诱导 DNA 损伤反应介导的严重脓毒症保护作用。
Immunity. 2013 Nov 14;39(5):874-84. doi: 10.1016/j.immuni.2013.08.039. Epub 2013 Oct 31.
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Severe sepsis and septic shock.严重脓毒症和脓毒性休克。
N Engl J Med. 2013 Aug 29;369(9):840-51. doi: 10.1056/NEJMra1208623.
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Disease tolerance as a defense strategy.疾病耐受力作为一种防御策略。
Science. 2012 Feb 24;335(6071):936-41. doi: 10.1126/science.1214935.