牵拉性脱发的组织病理学诊断：基于证据的模型。
The histopathologic diagnosis of traction alopecia: An evidence-based model.
机构信息
Dermatology and Dermatopathology, Geisinger Medical Center, Danville, Pennsylvania.
HCT Dermatopathology Services, Baltimore, Maryland; Department of Dermatology, Uniformed Services University, Bethesda, Maryland.
出版信息
J Am Acad Dermatol. 2023 Oct;89(4):745-749. doi: 10.1016/j.jaad.2023.05.094. Epub 2023 Jun 24.
BACKGROUND
Traction alopecia (TA) is common, but histopathologic criteria for TA have not been objectively defined.
OBJECTIVE
Determine whether the pauci-follicular unit (PFU) can be used as a diagnostic criterion for TA. Compared to a normal follicular unit (NFU), the PFU is a noninflamed follicular unit with an intact sebaceous gland but fewer than 2 follicles.
METHODS
A retrospective review of 25 cases of TA and 25 cases of "normal scalp" was performed. Data included all follicles (by size and phase), sebaceous glands, and total follicular units.
RESULTS
Comparing data (traction vs normal), we found a significantly higher number of PFUs in cases of TA (median 6 vs 0, P < .001), which can be used as a helpful and easily recognizable diagnostic tool in diagnosing cases of TA.
LIMITATIONS
Comparison to other forms of alopecia was not performed.
CONCLUSIONS
The number of PFUs in an alopecia biopsy can be used to establish the diagnosis of TA.
背景
牵引性脱发（TA）很常见，但 TA 的组织病理学标准尚未被客观定义。
目的
确定少毛囊单位（PFU）是否可以作为 TA 的诊断标准。与正常毛囊单位（NFU）相比，PFU 是一个非炎症性的毛囊单位，其皮脂腺完整，但毛囊少于 2 个。
方法
对 25 例 TA 和 25 例“正常头皮”进行回顾性研究。数据包括所有毛囊（按大小和阶段）、皮脂腺和总毛囊单位。
结果
比较牵引与正常组的数据，我们发现 TA 病例中 PFU 的数量明显更高（中位数 6 比 0，P<.001），这可以作为诊断 TA 的一种有用且易于识别的诊断工具。
局限性
未与其他形式的脱发进行比较。
结论
脱发活检中 PFU 的数量可用于确立 TA 的诊断。
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