Maruyama K, Tsuchihashi Y, Tani T, Yorioka S, Kodama T, Takino T, Ashihara T
Gan No Rinsho. 1986 Jun;32(7):769-78.
Twenty cases of the entire course of the large intestine were obtained from autopsy materials within four hours after death and examined histologically. The autolytic changes were found to be minimal and the mucosal architecture was fairly well preserved in our studies. The morphometric analysis showed that the glandular lengths in the rectosigmoid colon were greater than those of the other parts of the large intestine. Cystic dilatations of the glands were most frequently observed in the distal colon, and tended to occur in the vicinity of neoplastic changes. These results indicate that the hyperplastic changes of the glands, occasionally with cystic dilatations, are important as the background for the development of neoplastic diseases in the large intestine.
从死亡后四小时内的尸检材料中获取了20例大肠全段样本,并进行了组织学检查。在我们的研究中发现自溶变化极小,黏膜结构保存相当完好。形态计量分析表明,直肠乙状结肠的腺管长度大于大肠其他部位。腺管的囊性扩张最常出现在远端结肠,且倾向于发生在肿瘤性病变附近。这些结果表明,腺管的增生性变化,偶尔伴有囊性扩张,作为大肠肿瘤性疾病发生发展的背景具有重要意义。